Recombinant Mouse ST2/IL-33 R Fc Chimera Protein, CF

Name	Recombinant Mouse ST2/IL-33 R Fc Chimera Protein, CF
Supplier	R&D Systems
Catalog	1004-MR
Category	Protein
Prices	$329.00
Sizes	50 µg
Species Reactivities	Mouse
Nature	Recombinant
Source	Spodoptera frugiperda , Sf 21 (baculovirus)-derived Mouse ST2 (Ser27-Ser342) Accession # P14719 IEGRMD Human IgG 1 (Pro100-Lys330) N-terminus C-terminus
Purity	>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Bioactivity	Measured by its ability to bind Recombinant Mouse IL‑33 (Catalog # 3626-ML ) in a functional ELISA with an estimated K D < 50 nM. Schmitz, J. et al . (2005) Immunity 23 :479.
Endotoxin	<0.10 EU per 1 μg of the protein by the LAL method.
SwissProt/Accession	P14719
Gene	Il1rl1
Sequence	Ser27
Supplier Page	Shop

Product References

IL-33 ameliorates Alzheimer's disease-like pathology and cognitive decline. - IL-33 ameliorates Alzheimer's disease-like pathology and cognitive decline.

Fu AK, Hung KW, Yuen MY, Zhou X, Mak DS, Chan IC, Cheung TH, Zhang B, Fu WY, Liew FY, Ip NY. Proc Natl Acad Sci U S A. 2016 May 10;113(19):E2705-13. doi:

Aspirin-Exacerbated Respiratory Disease Involves a Cysteinyl Leukotriene-Driven - Aspirin-Exacerbated Respiratory Disease Involves a Cysteinyl Leukotriene-Driven

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A robust high throughput platform to generate functional recombinant monoclonal - A robust high throughput platform to generate functional recombinant monoclonal

Seeber S, Ros F, Thorey I, Tiefenthaler G, Kaluza K, Lifke V, Fischer JA, Klostermann S, Endl J, Kopetzki E, Pashine A, Siewe B, Kaluza B, Platzer J, Offner S. PLoS One. 2014 Feb 4;9(2):e86184.

Transcription factor IRF4 drives dendritic cells to promote Th2 differentiation. - Transcription factor IRF4 drives dendritic cells to promote Th2 differentiation.

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The receptor tyrosine kinase c-Kit controls IL-33 receptor signaling in mast - The receptor tyrosine kinase c-Kit controls IL-33 receptor signaling in mast

Drube S, Heink S, Walter S, Lohn T, Grusser M, Gerbaulet A, Berod L, Schons J, Dudeck A, Freitag J, Grotha S, Reich D, Rudeschko O, Norgauer J, Hartmann K, Roers A, Kamradt T. Blood. 2010 May 13;115(19):3899-906.

IL-1 receptor accessory protein is essential for IL-33-induced activation of T - IL-1 receptor accessory protein is essential for IL-33-induced activation of T

Ali S, Huber M, Kollewe C, Bischoff SC, Falk W, Martin MU. Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18660-5. Epub 2007 Nov 14.

IL-1 receptor accessory protein and ST2 comprise the IL-33 receptor complex. - IL-1 receptor accessory protein and ST2 comprise the IL-33 receptor complex.

Chackerian AA, Oldham ER, Murphy EE, Schmitz J, Pflanz S, Kastelein RA. J Immunol. 2007 Aug 15;179(4):2551-5.