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Ah Receptor Antibody (A-3) is a mouse monoclonal IgG2b kappa light chain antibody that detects aryl hydrocarbon receptor protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Aryl hydrocarbon receptor antibody (A-3) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. The aryl hydrocarbon receptor (AhR) plays a crucial role in mediating the biological effects of environmental toxins, such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), which is known to induce adverse reproductive, immunologic, and metabolic effects. As a ligand-dependent transcription factor, AhR is essential for regulating the expression of genes involved in xenobiotic metabolism. Upon binding to TCDD or other ligands, AhR forms a complex with the Ah Receptor nuclear translocator (Arnt), facilitating its translocation to the nucleus where it binds to specific DNA sequences known as xenobiotic responsive elements (XREs). This interaction is vital for the transcriptional activation of genes that help detoxify harmful compounds, underscoring the importance of AhR in maintaining cellular homeostasis and responding to environmental stressors.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ah Receptor Antibody (A-3) | sc-133088 | 200 µg/ml | $316.00 | |||
Ah Receptor Antibody (A-3): m-IgGκ BP-HRP Bundle | sc-521229 | 200 µg Ab, 40 µg BP | $354.00 | |||
Ah Receptor Antibody (A-3): m-IgG2b BP-HRP Bundle | sc-548874 | 200 µg Ab; 10 µg BP | $354.00 | |||
Ah Receptor Antibody (A-3) X | sc-133088 X | 200 µg/0.1 ml | $316.00 | |||
Ah Receptor Antibody (A-3) AC | sc-133088 AC | 500 µg/ml, 25% agarose | $416.00 | |||
Ah Receptor Antibody (A-3) HRP | sc-133088 HRP | 200 µg/ml | $316.00 | |||
Ah Receptor Antibody (A-3) FITC | sc-133088 FITC | 200 µg/ml | $330.00 | |||
Ah Receptor Antibody (A-3) PE | sc-133088 PE | 200 µg/ml | $343.00 | |||
Ah Receptor Antibody (A-3) Alexa Fluor® 488 | sc-133088 AF488 | 200 µg/ml | $357.00 | |||
Ah Receptor Antibody (A-3) Alexa Fluor® 546 | sc-133088 AF546 | 200 µg/ml | $357.00 | |||
Ah Receptor Antibody (A-3) Alexa Fluor® 594 | sc-133088 AF594 | 200 µg/ml | $357.00 | |||
Ah Receptor Antibody (A-3) Alexa Fluor® 647 | sc-133088 AF647 | 200 µg/ml | $357.00 | |||
Ah Receptor Antibody (A-3) Alexa Fluor® 680 | sc-133088 AF680 | 200 µg/ml | $357.00 | |||
Ah Receptor Antibody (A-3) Alexa Fluor® 790 | sc-133088 AF790 | 200 µg/ml | $357.00 |