CSA Antibody (235C3a): sc-81560
- CSA Antibody (235C3a) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against a recombinant protein corresponding to an internal region of CSA of human origin
- recommended for detection of CSA of human origin by WB and IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CSA Antibody (235C3a). This work is in progress.
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CSA Antibody (235C3a) is a mouse monoclonal IgG1 antibody that detects CSA in human samples through applications such as western blotting (WB) and immunoprecipitation (IP). CSA, a crucial protein in the nucleotide excision repair pathway, plays a significant role in the preferential repair of DNA lesions on the transcribed strand, which is vital for maintaining genomic stability and preventing mutations that can lead to diseases such as Cockayne′s syndrome. This syndrome is characterized by defects in the repair of active genes, resulting from mutations in the CSA and CSB genes, which are essential for directing the transcription-coupled repair process. CSA belongs to the "WD-repeat" family of proteins, which are known for their involvement in various cellular processes, including signal transduction and gene regulation. Anti-CSA antibody (235C3a) ensures that DNA repair mechanisms are efficiently targeted to the areas of the genome that are actively being transcribed, thereby safeguarding the integrity of essential genes. CSA monoclonal antibody (235C3a) serves as an invaluable tool for researchers studying the mechanisms of DNA repair and the implications of its dysfunction in human diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CSA Antibody (235C3a) | sc-81560 | 100 µg/ml | $333.00 |