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p-IκB-α Antibody (39A1431) is a mouse monoclonal IgG1 antibody that detects p-IκB-α in mouse, rat, and human samples through western blotting (WB). p-IκB-α plays a crucial role in regulating the NF-κB signaling pathway, which controls various cellular processes, including inflammation, immune response, and cell survival. Phosphorylation of IκB-α leads to inhibitor degradation, allowing NF-κB dimers to translocate to the nucleus and activate target genes. This post-translational modification enables timely and appropriate responses to cellular stress and inflammatory signals, making p-IκB-α a key player in maintaining cellular homeostasis. p-IκB-α (39A1431) monoclonal antibody provides reliable detection of phosphorylated IκB-α, enabling researchers to study its role in various biological contexts and disease states, particularly those related to dysregulated NF-κB activity.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
p-NFKBIA/IkB alpha Antibody (39A1431) | sc-52943 | 50 µg/0.5 ml | $316.00 |