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Smad4 Antibodies

Santa Cruz Biotechnology delivers a wide array of Smad4 monoclonal antibodies for advanced research in cellular signaling pathways. Smad4 Antibodies are validated for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Smad4 is a critical mediator in the transforming growth factor-beta (TGF-β) signaling pathway, playing a vital role in regulating cell growth, differentiation, and apoptosis. Its function is essential for maintaining cellular homeostasis and has significant implications in developmental processes and cancer biology. Dysregulation of Smad4 has been associated with various diseases, highlighting its importance as a target for therapeutic intervention. Researchers can explore the molecular mechanisms of Smad4 through multiple experimental approaches, from protein detection to cellular localization studies. Understanding Smad4's role in TGF-β signaling provides valuable insights into disease mechanisms and potential therapeutic strategies. Santa CruzBiotechnology monoclonal antibodies enable researchers worldwide to advance their understanding of cellular signaling pathways and contribute to scientific discoveries.

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Smad4 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Smad4 Antibody (B-8)

sc-7966mouse IgG1 κFL (h)WB, IP, IF, IHC(P), FCM, ELISAm, r, h
820
(40)

Smad4 Antibody (0.N.557)

sc-73040mouse IgG1 κ(h)WB, IP, IF, IHC(P)m, r, h
4
(2)

Smad4 Antibody (DCS-46)

sc-73599mouse IgG1 κ(h)WB, IP, IF, IHC(P)m, r, h
2
(1)

Smad4 Antibody (SMD46)

sc-56775mouse IgG1 κ(h)WB, IP, IF, IHC(P)m, r, h

new

(1)

Smad4 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Smad4 CRISPR/Cas9 KO Plasmid (h)

sc-400110hGene KnockoutGFP
2
(0)

Smad4 HDR Plasmid (h)

sc-400110-HDRhHomology Directed RepairPuromycin
2
(0)

Smad4 Double Nickase Plasmid (h)

sc-400110-NIChGene KnockoutPuromycin
2
(0)

Smad4 Double Nickase Plasmid (h2)

sc-400110-NIC-2hGene KnockoutPuromycin
2
(0)

Smad4 CRISPR/Cas9 KO Plasmid (m)

sc-421527mGene KnockoutGFP0
(0)

Smad4 HDR Plasmid (m)

sc-421527-HDRmHomology Directed RepairPuromycin0
(0)

Smad4 Double Nickase Plasmid (m)

sc-421527-NICmGene KnockoutPuromycin0
(0)

Smad4 Double Nickase Plasmid (m2)

sc-421527-NIC-2mGene KnockoutPuromycin0
(0)

Smad4 CRISPR Activation Products

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Smad4 CRISPR Activation Plasmid (h)

sc-400110-ACThGene ActivationPuro, Blast, Hygro
2
(0)

Smad4 CRISPR Activation Plasmid (h2)

sc-400110-ACT-2hGene ActivationPuro, Blast, Hygro
2
(0)

Smad4 Lentiviral Activation Particles (h)

sc-400110-LAChGene ActivationPuro, Blast, Hygro
2
(0)

Smad4 Lentiviral Activation Particles (h2)

sc-400110-LAC-2hGene ActivationPuro, Blast, Hygro
2
(0)

Smad4 CRISPR Activation Plasmid (m)

sc-421527-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Smad4 CRISPR Activation Plasmid (m2)

sc-421527-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Smad4 Lentiviral Activation Particles (m)

sc-421527-LACmGene ActivationPuro, Blast, Hygro0
(0)

Smad4 Lentiviral Activation Particles (m2)

sc-421527-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Smad4 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Smad4 siRNA (h)

sc-29484hGene SilencingN/A
26
(1)

Smad4 shRNA Plasmid (h)

sc-29484-SHhGene SilencingPuromycin
26
(1)

Smad4 shRNA (h) Lentiviral Particles

sc-29484-VhGene SilencingPuromycin
26
(1)

Smad4 siRNA (m)

sc-29485mGene SilencingN/A
5
(0)

Smad4 siRNA (m2)

sc-44274mGene SilencingN/A0
(0)

Smad4 shRNA Plasmid (m)

sc-29485-SHmGene SilencingPuromycin
5
(0)

Smad4 shRNA Plasmid (m2)

sc-44274-SHmGene SilencingPuromycin0
(0)

Smad4 shRNA (m) Lentiviral Particles

sc-29485-VmGene SilencingPuromycin
5
(0)

Smad4 shRNA (m2) Lentiviral Particles

sc-44274-VmGene SilencingPuromycin0
(0)

Smad4 siRNA (r)

sc-270254rGene SilencingN/A
1
(0)

Smad4 shRNA Plasmid (r)

sc-270254-SHrGene SilencingPuromycin
1
(0)

Smad4 shRNA (r) Lentiviral Particles

sc-270254-VrGene SilencingPuromycin
1
(0)