PPARγ Antibody (8D1H8H4): sc-81152
- PPARγ Antibody (8D1H8H4) is a mouse monoclonal IgG1, cited in 11 publications, provided at 200 µg/ml
- raised against a recombinant protein corresponding to amino acids 77-272 of PPARγ of human origin
- recommended for detection of PPARγ of mouse, rat and human origin by WB, IF and IHC(P)
- See PPARγ (E-8): sc-7273 for PPARγ antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for PPARγ Antibody (8D1H8H4). This work is in progress.
PPARγ Antibody (8D1H8H4) is a mouse monoclonal IgG1 antibody that detects PPARγ in mouse, rat, and human samples through applications such as western blotting (WB), immunofluorescence (IF), and immunohistochemistry. PPARγ, a member of the nuclear hormone receptor superfamily, plays a crucial role in regulating adipocyte differentiation and lipid metabolism, making PPARγ essential for maintaining energy homeostasis and metabolic health. PPARγ is primarily located in the nucleus, where PPARγ functions as a transcription factor that forms heterodimers with retinoid X receptors (RXRs) to modulate the expression of genes involved in insulin sensitivity and inflammation. Nuclear localization of PPARγ is vital, as this positioning allows for precise regulation of gene transcription in response to various ligands, including fatty acids and thiazolidinediones, which activate PPARγ and influence metabolic processes. Dysregulation of PPARγ has been implicated in several metabolic disorders, including obesity and type 2 diabetes, highlighting PPARγ′s importance as a therapeutic target. Anti-PPARγ antibody (8D1H8H4) is an invaluable tool for researchers studying the intricate roles of PPARγ in metabolic regulation and potential implications in disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PPARγ Antibody (8D1H8H4) | sc-81152 | 200 µg/ml | $316.00 |