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Atm Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of Atm Antibodies for various research applications. Atm Antibodies are compatible with western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Ataxia-telangiectasia mutated (ATM) is a critical protein involved in the cellular response to DNA damage, playing a key role in maintaining genomic stability. ATM is essential for the activation of DNA repair pathways and is implicated in cell cycle regulation. Mutations in the ATM gene are associated with ataxia-telangiectasia, a disorder characterized by neurodegeneration, immunodeficiency, and increased cancer risk. ATM signaling pathways are crucial for understanding cellular responses to DNA damage and potential therapeutic interventions. Research utilizing ATM monoclonal antibodies has revealed significant insights into DNA damage response mechanisms and cell cycle checkpoints. Investigating ATM's role in various cellular processes continues to advance our understanding of cancer biology and genetic disorders. Santa Cruz Biotechnology monoclonal antibodies for ATM research support scientists in advancing knowledge of DNA damage response pathways and potential therapeutic strategies.

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Atm Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Atm Antibody (G-12)

sc-377293mouse IgG1 κ2581-2860 (h)WB, IP, IF, IHC(P), ELISAh
29
(22)

Atm Antibody (ATM 11G12)

sc-53173mouse IgG1 κ992-1144 (h)WB, IP, IFh
9
(3)

Phospho-Specific Atm Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

p-Atm Antibody (10H11.E12)

sc-47739mouse IgG1 κSer 1981 (h)WB, IP, IF, IHC(P)m, r, h
122
(20)

Atm CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Atm CRISPR/Cas9 KO Plasmid (h)

sc-400192hGene KnockoutGFP
4
(0)

Atm HDR Plasmid (h)

sc-400192-HDRhHomology Directed RepairPuromycin
4
(0)

Atm Double Nickase Plasmid (h)

sc-400192-NIChGene KnockoutPuromycin
4
(0)

Atm Double Nickase Plasmid (h2)

sc-400192-NIC-2hGene KnockoutPuromycin
4
(0)

Atm CRISPR/Cas9 KO Plasmid (m)

sc-419229mGene KnockoutGFP0
(0)

Atm HDR Plasmid (m)

sc-419229-HDRmHomology Directed RepairPuromycin0
(0)

Atm Double Nickase Plasmid (m)

sc-419229-NICmGene KnockoutPuromycin0
(0)

Atm Double Nickase Plasmid (m2)

sc-419229-NIC-2mGene KnockoutPuromycin0
(0)

Atm CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Atm CRISPR Activation Plasmid (h)

sc-400192-ACThGene ActivationPuro, Blast, Hygro
4
(0)

Atm CRISPR Activation Plasmid (h2)

sc-400192-ACT-2hGene ActivationPuro, Blast, Hygro
4
(0)

Atm Lentiviral Activation Particles (h)

sc-400192-LAChGene ActivationPuro, Blast, Hygro
4
(0)

Atm Lentiviral Activation Particles (h2)

sc-400192-LAC-2hGene ActivationPuro, Blast, Hygro
4
(0)

Atm CRISPR Activation Plasmid (m)

sc-419229-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Atm CRISPR Activation Plasmid (m2)

sc-419229-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Atm Lentiviral Activation Particles (m)

sc-419229-LACmGene ActivationPuro, Blast, Hygro0
(0)

Atm Lentiviral Activation Particles (m2)

sc-419229-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Atm siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Atm siRNA (h)

sc-29761hGene SilencingN/A
49
(0)

Atm shRNA Plasmid (h)

sc-29761-SHhGene SilencingPuromycin
49
(0)

Atm shRNA (h) Lentiviral Particles

sc-29761-VhGene SilencingPuromycin
49
(0)

Atm siRNA (m)

sc-29762mGene SilencingN/A
8
(0)

Atm shRNA Plasmid (m)

sc-29762-SHmGene SilencingPuromycin
8
(0)

Atm shRNA (m) Lentiviral Particles

sc-29762-VmGene SilencingPuromycin
8
(0)