PAcP Antibody (C-12): sc-390564
- PAcP Antibody (C-12) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 146-260 mapping within an internal region of PAcP of human origin
- recommended for detection of PAcP of human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for PAcP Antibody (C-12) for WB applications. These reagents are now offered in bundles with PAcP Antibody (C-12) (see ordering information below).
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SEE ALSO...
PAcP Antibody (C-12) is a mouse monoclonal IgG1 antibody that detects prostatic acid phosphatase (PAcP) in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PAcP functions as a neutral protein-tyrosine phosphatase, primarily regulating prostate cell growth by catalyzing the conversion of orthophosphoric monoester to alcohol and orthophosphate. Androgen regulation of PAcP enzymatic activity leads to stimulated secretion, serving as a hallmark of androgen action on human prostate epithelial cells. PAcP down-regulates prostate cancer cell growth, partly by dephosphorylating c-ErbB-2/neu, making PAcP a potential biomarker for prostate cancer progression, as decreased cellular PAcP expression in cancer cells may contribute to tumor development. PAcP is encoded by the human ACPP gene, located on chromosome 3q21-q23, making PAcP a valuable target for research into prostate health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PAcP Antibody (C-12) | sc-390564 | 200 µg/ml | $316.00 | |||
PAcP Antibody (C-12): m-IgG Fc BP-HRP Bundle | sc-540818 | 200 µg Ab; 10 µg BP | $354.00 | |||
PAcP Antibody (C-12): m-IgG1 BP-HRP Bundle | sc-542391 | 200 µg Ab; 20 µg BP | $354.00 |