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PI 3-kinase p55γ Antibody (E-9) is a mouse monoclonal IgG1 kappa light chain antibody that detects PI 3-kinase p55 gamma of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PI 3-kinase p55γ (E-9) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. PI 3-kinase p55 gamma plays a crucial role in cellular signaling pathways, particularly in regulating cell growth, proliferation, and survival, making PI 3-kinase p55 gamma a significant target for cancer research and therapeutic interventions. PI 3-kinase p55 gamma is primarily located in the cytoplasm and translocates to the plasma membrane upon activation, where PI 3-kinase p55 gamma interacts with phosphatidylinositol 4,5-bisphosphate to initiate downstream signaling cascades. Proper localization of PI 3-kinase p55 gamma is essential for function, as mislocalization can lead to aberrant signaling and contribute to various diseases, including cancer. Human PI 3-kinase p55 gamma consists of a unique amino terminal region, a proline-rich motif, and two Src homology 2 (SH2) domains, which are critical for interaction with other signaling molecules. Research indicates that PI 3-kinase p55 gamma interacts with insulin-like growth factor-I receptor and insulin receptor, suggesting involvement in PI 3-kinase activation by these receptors.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PI 3-kinase p55γ Antibody (E-9) | sc-376615 | 200 µg/ml | $316.00 | |||
PI 3-kinase p55γ Antibody (E-9): m-IgG Fc BP-HRP Bundle | sc-527542 | 200 µg Ab; 10 µg BP | $354.00 | |||
PI 3-kinase p55γ Antibody (E-9): m-IgG1 BP-HRP Bundle | sc-532915 | 200 µg Ab; 20 µg BP | $354.00 | |||
PI 3-kinase p55γ Antibody (E-9) AC | sc-376615 AC | 500 µg/ml, 25% agarose | $416.00 | |||
PI 3-kinase p55γ Antibody (E-9) HRP | sc-376615 HRP | 200 µg/ml | $316.00 | |||
PI 3-kinase p55γ Antibody (E-9) FITC | sc-376615 FITC | 200 µg/ml | $330.00 | |||
PI 3-kinase p55γ Antibody (E-9) PE | sc-376615 PE | 200 µg/ml | $343.00 | |||
PI 3-kinase p55γ Antibody (E-9) Alexa Fluor® 488 | sc-376615 AF488 | 200 µg/ml | $357.00 | |||
PI 3-kinase p55γ Antibody (E-9) Alexa Fluor® 546 | sc-376615 AF546 | 200 µg/ml | $357.00 | |||
PI 3-kinase p55γ Antibody (E-9) Alexa Fluor® 594 | sc-376615 AF594 | 200 µg/ml | $357.00 | |||
PI 3-kinase p55γ Antibody (E-9) Alexa Fluor® 647 | sc-376615 AF647 | 200 µg/ml | $357.00 | |||
PI 3-kinase p55γ Antibody (E-9) Alexa Fluor® 680 | sc-376615 AF680 | 200 µg/ml | $357.00 | |||
PI 3-kinase p55γ Antibody (E-9) Alexa Fluor® 790 | sc-376615 AF790 | 200 µg/ml | $357.00 |