PP2B-B1/2 Antibody (D-1): sc-373803
- PP2B-B1/2 Antibody (D-1) is a mouse monoclonal IgG2b κ PP2B-B1/2 antibody, cited in 3 publications, provided at 200 µg/ml
- raised against amino acids 1-170 representing full length PP2B-B2 of human origin
- PP2B-B1/2 Antibody (D-1) is recommended for detection of PP2B-B1 and PP2B-B2 of human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-PP2B-B1/2 Antibody (D-1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of PP2B-B1/2 (D-1): sc-373803.
- m-IgGκ BP-HRP is the preferred secondary detection reagent for PP2B-B1/2 Antibody (D-1) for WB and IHC(P) applications. This reagent is now offered in a bundle with PP2B-B1/2 Antibody (D-1) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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SEE ALSO...
PP2B-B1/2 Antibody (D-1) is a mouse monoclonal IgG2b kappa light chain antibody that detects PP2B-B1/2 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). PP2B-B1/2 (D-1) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. PP2B-B1/2 plays a crucial role in regulating cellular signaling pathways through function as a protein phosphatase, specifically involved in dephosphorylating serine and threonine residues. This activity maintains cellular homeostasis, regulates cell division, and controls apoptosis, making PP2B-B1/2 significant in various physiological processes. PP2B-B1/2 belongs to a larger family of protein phosphatases, essential for reversing kinase actions and modulating target protein phosphorylation states. The PP2B family, including subfamily members PP2B-Aα, PP2B-Aβ, and PP2B-Aγ, is particularly important in calcium signaling and immune responses. Understanding PP2B-B1/2 interactions and regulatory mechanisms provides insights into health and disease, highlighting potential therapeutic applications in various conditions.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
PP2B-B1/2 Antibody (D-1) References:
- Structure and expression of two isoforms of the murine calmodulin-dependent protein phosphatase regulatory subunit (calcineurin B). | Ueki, K., et al. 1992. Biochem Biophys Res Commun. 187: 537-43. PMID: 1325794
- Molecular cloning of NIPP-1, a nuclear inhibitor of protein phosphatase-1, reveals homology with polypeptides involved in RNA processing. | Van Eynde, A., et al. 1995. J Biol Chem. 270: 28068-74. PMID: 7499293
- Serine/threonine protein phosphatases. | Wera, S. and Hemmings, BA. 1995. Biochem J. 311 (Pt 1): 17-29. PMID: 7575450
- Important roles for novel protein phosphatases dephosphorylating serine and threonine residues. | Cohen, PT. 1993. Biochem Soc Trans. 21: 884-8. PMID: 8132087
- A regulatory subunit of smooth muscle myosin bound phosphatase. | Okubo, S., et al. 1994. Biochem Biophys Res Commun. 200: 429-34. PMID: 8166716
- Structure and expression of a 72-kDa regulatory subunit of protein phosphatase 2A. Evidence for different size forms produced by alternative splicing. | Hendrix, P., et al. 1993. J Biol Chem. 268: 15267-76. PMID: 8392071
- Protein serine/threonine phosphatases: structure, regulation, and functions in cell growth. | Mumby, MC. and Walter, G. 1993. Physiol Rev. 73: 673-99. PMID: 8415923
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PP2B-B1/2 Antibody (D-1) | sc-373803 | 200 µg/ml | $316.00 | |||
PP2B-B1/2 Antibody (D-1): m-IgGκ BP-HRP Bundle | sc-522505 | 200 µg Ab, 40 µg BP | $354.00 | |||
PP2B-B1/2 Antibody (D-1) AC | sc-373803 AC | 500 µg/ml, 25% agarose | $416.00 | |||
PP2B-B1/2 Antibody (D-1) HRP | sc-373803 HRP | 200 µg/ml | $316.00 | |||
PP2B-B1/2 Antibody (D-1) FITC | sc-373803 FITC | 200 µg/ml | $330.00 | |||
PP2B-B1/2 Antibody (D-1) PE | sc-373803 PE | 200 µg/ml | $343.00 | |||
PP2B-B1/2 Antibody (D-1) Alexa Fluor® 488 | sc-373803 AF488 | 200 µg/ml | $357.00 | |||
PP2B-B1/2 Antibody (D-1) Alexa Fluor® 546 | sc-373803 AF546 | 200 µg/ml | $357.00 | |||
PP2B-B1/2 Antibody (D-1) Alexa Fluor® 594 | sc-373803 AF594 | 200 µg/ml | $357.00 | |||
PP2B-B1/2 Antibody (D-1) Alexa Fluor® 647 | sc-373803 AF647 | 200 µg/ml | $357.00 | |||
PP2B-B1/2 Antibody (D-1) Alexa Fluor® 680 | sc-373803 AF680 | 200 µg/ml | $357.00 | |||
PP2B-B1/2 Antibody (D-1) Alexa Fluor® 790 | sc-373803 AF790 | 200 µg/ml | $357.00 |