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Pyridoxal phosphatase Antibody (A-11) is a mouse monoclonal IgG1 antibody that detects pyridoxal phosphatase in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Pyridoxal phosphatase, comprising 296 amino acids, plays a crucial role in the metabolism of vitamin B6 by catalyzing the dephosphorylation of pyridoxal 5′-phosphate, the active form of this essential vitamin. This enzymatic activity is vital for the synthesis of neurotransmitters, including serotonin and gamma-aminobutyric acid, which are critical for proper brain function and mood regulation. High expression of pyridoxal phosphatase in various regions of the central nervous system, particularly the brain, underscores pyridoxal phosphatase′s importance in neurological health. Additionally, autoantibodies against pyridoxal phosphatase have been linked to certain cancer types, highlighting pyridoxal phosphatase′s potential as a biomarker for disease. Anti-pyridoxal phosphatase antibody (A-11) serves as an invaluable tool for researchers investigating pyridoxal phosphatase′s role in both normal physiology and pathological conditions.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
pyridoxal phosphatase Antibody (A-11) | sc-271073 | 200 µg/ml | $316.00 | |||
pyridoxal phosphatase Antibody (A-11): m-IgG1 BP-HRP Bundle | sc-542677 | 200 µg Ab; 20 µg BP | $354.00 |