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pyridoxal phosphatase Antibody (A-11): sc-271073

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Datasheets
  • pyridoxal phosphatase Antibody (A-11) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
  • raised against amino acids 158-197 mapping within an internal region of pyridoxal phosphatase of human origin
  • recommended for detection of pyridoxal phosphatase of human origin by WB, IP, IF and ELISA
  • m-IgG1 BP-HRP is the preferred secondary detection reagent for pyridoxal phosphatase Antibody (A-11) for WB applications. This reagent is now offered in a bundle with pyridoxal phosphatase Antibody (A-11) (see ordering information below).

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    Pyridoxal phosphatase Antibody (A-11) is a mouse monoclonal IgG1 antibody that detects pyridoxal phosphatase in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Pyridoxal phosphatase, comprising 296 amino acids, plays a crucial role in the metabolism of vitamin B6 by catalyzing the dephosphorylation of pyridoxal 5′-phosphate, the active form of this essential vitamin. This enzymatic activity is vital for the synthesis of neurotransmitters, including serotonin and gamma-aminobutyric acid, which are critical for proper brain function and mood regulation. High expression of pyridoxal phosphatase in various regions of the central nervous system, particularly the brain, underscores pyridoxal phosphatase′s importance in neurological health. Additionally, autoantibodies against pyridoxal phosphatase have been linked to certain cancer types, highlighting pyridoxal phosphatase′s potential as a biomarker for disease. Anti-pyridoxal phosphatase antibody (A-11) serves as an invaluable tool for researchers investigating pyridoxal phosphatase′s role in both normal physiology and pathological conditions.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    pyridoxal phosphatase Antibody (A-11)

    sc-271073
    200 µg/ml
    $316.00

    pyridoxal phosphatase Antibody (A-11): m-IgG1 BP-HRP Bundle

    sc-542677
    200 µg Ab; 20 µg BP
    $354.00

    What blocking solution should I use with pyridoxal phosphatase (A-11): sc-271073 monoclonal antibody for Western blot?

    Asked by: TinTin
    Thank you for your question. We recommend blocking with Blotto (either TBS Blotto A: sc-2333 or TBS Blotto B: sc-2335). Our Western blot protocol can be found here: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
    Answered by: Technical Support
    Date published: 2017-03-01
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    Rated 5 out of 5 by from Produced positive Western blot data of pyridoxalProduced positive Western blot data of pyridoxal phosphatase expression in non-transfected and human pyridoxal phosphatase transfected 293T whole cell lysates. -SCBT QC
    Date published: 2014-10-08
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    pyridoxal phosphatase Antibody (A-11) is rated 5.0 out of 5 by 1.
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