ephrin-A5 Antibody (RR-7): sc-81945

ephrin-A5 Antibody (RR-7) is a mouse monoclonal IgG2a kappa light chain antibody that detects ephrin-A5 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). anti-ephrin-A5 antibody (RR-7) is available as a non-conjugated format, providing researchers with a reliable tool for studying this important protein. Ephrin-A5 plays a crucial role in cell signaling and communication, particularly in the development and function of the central nervous system. Ephrin-A5 interacts with EphA5 receptors, which are involved in various processes such as neuronal development, axon guidance, and synaptic plasticity. The interaction between ephrin-A5 and EphA5 receptors is essential for establishing proper neural connections, and disruptions in this signaling pathway have been implicated in neurological disorders. Understanding the dynamics of ephrin-A5 and EphA5 receptor interactions can provide valuable insights into the mechanisms underlying brain development and function, making ephrin-A5 (RR-7) monoclonal antibody an essential reagent for researchers investigating these critical biological processes.

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ephrin-A5 Antibody (RR-7) References:

1. Ephrin-A2 and ephrin-A5 guide contralateral targeting but not topographic mapping of ventral cochlear nucleus axons.  |  Abdul-Latif, ML., et al. 2015. Neural Dev. 10: 27. PMID: 26666565
2. Abnormal expression of ephrin-A5 affects brain development of congenital hypothyroidism rats.  |  Suo, G., et al. 2018. Neuroreport. 29: 877-882. PMID: 29762250
3. Reduction of ephrin-A5 aggravates disease progression in amyotrophic lateral sclerosis.  |  Rué, L., et al. 2019. Acta Neuropathol Commun. 7: 114. PMID: 31300041
4. Ephrin-A5 potentiates netrin-1 axon guidance by enhancing Neogenin availability.  |  Croteau, LP., et al. 2019. Sci Rep. 9: 12009. PMID: 31427645
5. ADAM10-cleaved ephrin-A5 contributes to prostate cancer metastasis.  |  Cai, C., et al. 2022. Cell Death Dis. 13: 453. PMID: 35551177
6. Identification and cloning of ELF-1, a developmentally expressed ligand for the Mek4 and Sek receptor tyrosine kinases.  |  Cheng, HJ. and Flanagan, JG. 1994. Cell. 79: 157-68. PMID: 7522971
7. ELF-2, a new member of the Eph ligand family, is segmentally expressed in mouse embryos in the region of the hindbrain and newly forming somites.  |  Bergemann, AD., et al. 1995. Mol Cell Biol. 15: 4921-9. PMID: 7651410
8. Cloning of AL-1, a ligand for an Eph-related tyrosine kinase receptor involved in axon bundle formation.  |  Winslow, JW., et al. 1995. Neuron. 14: 973-81. PMID: 7748564
9. Ligands for the receptor tyrosine kinases hek and elk: isolation of cDNAs encoding a family of proteins.  |  Kozlosky, CJ., et al. 1995. Oncogene. 10: 299-306. PMID: 7838529
10. Molecular characterization of a family of ligands for eph-related tyrosine kinase receptors.  |  Beckmann, MP., et al. 1994. EMBO J. 13: 3757-62. PMID: 8070404
11. B61 is a ligand for the ECK receptor protein-tyrosine kinase.  |  Bartley, TD., et al. 1994. Nature. 368: 558-60. PMID: 8139691
12. Elk-L3, a novel transmembrane ligand for the Eph family of receptor tyrosine kinases, expressed in embryonic floor plate, roof plate and hindbrain segments.  |  Gale, NW., et al. 1996. Oncogene. 13: 1343-52. PMID: 8808709

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-ephrin-A5 Antibody (RR-7) has 3 citations in a variety of scientific publications.

Primary antibodies like Anti-ephrin-A5 Antibody (RR-7) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

ephrin-A5 Antibody (RR-7) Specifications

Alternate Product Name: ephrin-A5

Product Clone Name: RR-7

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids: 114-204

Epitope Target: ephrin-A5

Epitope Species: human

Product Reactivity/Detection: ephrin-A5

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, ELISA

Vialing Information: Each vial contains 100 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 3 citations in various scientific publications

Available Conjugates/Forms for ephrin-A5 Antibody (RR-7): N/A