ephrin-B3 Antibody (A-7): sc-271328
- ephrin-B3 Antibody (A-7) is a mouse monoclonal IgG1 κ, cited in 3 publications, provided at 200 µg/ml
- raised against amino acids 141-310 mapping near the C-terminus of ephrin-B3 of human origin
- recommended for detection of ephrin-B3 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ephrin-B3 Antibody (A-7) for WB applications. These reagents are now offered in bundles with ephrin-B3 Antibody (A-7) (see ordering information below).
ephrin-B3 Antibody (A-7) is a mouse monoclonal IgG1 antibody that detects ephrin-B3 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Ephrin-B3 plays a crucial role in cell signaling and communication, particularly in nervous system development, where ephrin-B3 regulates neuronal growth and guidance. Anti-ephrin-B3 antibody (A-7) targets this protein on the cell surface, where ephrin-B3 interacts with Eph receptors, facilitating bidirectional signaling that influences cellular processes such as migration, adhesion, and differentiation. Ephrin-B3′s location on the cell surface enables critical interactions with Eph receptors, essential for establishing proper neural connections during development and maintaining synaptic plasticity in the adult brain. Ephrin-B3 participates in various physiological and pathological processes, including angiogenesis and tumor progression, making ephrin-B3 monoclonal antibody (A-7) an invaluable tool for researchers exploring cellular communication and its implications in health and disease.
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ephrin-B3 Antibody (A-7) References:
- Ephrin-B3 binds specifically to B lymphocytes in blood and induces migration. | Holen, HL., et al. 2011. Scand J Immunol. 74: 144-54. PMID: 21447033
- Ephrin-B2 and ephrin-B3 as functional henipavirus receptors. | Xu, K., et al. 2012. Semin Cell Dev Biol. 23: 116-23. PMID: 22227101
- Ephrin-B3 recruits PSD-95 to synapses. | Fei, E., et al. 2015. Nat Neurosci. 18: 1535-7. PMID: 26505562
- Ephrin-B3 coordinates timed axon targeting and amygdala spinogenesis for innate fear behaviour. | Zhu, XN., et al. 2016. Nat Commun. 7: 11096. PMID: 27008987
- Ephrin-B3 supports glioblastoma growth by inhibiting apoptosis induced by the dependence receptor EphA4. | Royet, A., et al. 2017. Oncotarget. 8: 23750-23759. PMID: 28423606
- Ephrin‑b3 modulates hippocampal neurogenesis and the reelin signaling pathway in a pilocarpine‑induced model of epilepsy. | Liu, TT., et al. 2018. Int J Mol Med. 41: 3457-3467. PMID: 29512697
- Ephrin-B3 binds both cell-associated and secreted proteoglycans. | Prydz, K., et al. 2018. Biochem Biophys Res Commun. 503: 2212-2217. PMID: 29953858
- Natural loss of function of ephrin-B3 shapes spinal flight circuitry in birds. | Haimson, B., et al. 2021. Sci Adv. 7: PMID: 34117069
- Activation of spinal ephrin-B3/EphBs signaling induces hyperalgesia through a PLP-mediated mechanism. | Zhang, P., et al. 2022. Fundam Clin Pharmacol. 36: 262-276. PMID: 34904278
- Ephrin B3 exacerbates colitis and colitis-associated colorectal cancer. | Qiao, Z., et al. 2024. Biochem Pharmacol. 220: 116004. PMID: 38142837
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ephrin-B3 Antibody (A-7) | sc-271328 | 200 µg/ml | $316.00 | |||
ephrin-B3 Antibody (A-7): m-IgG Fc BP-HRP Bundle | sc-537611 | 200 µg Ab; 10 µg BP | $354.00 | |||
ephrin-B3 Antibody (A-7): m-IgGκ BP-HRP Bundle | sc-534928 | 200 µg Ab; 40 µg BP | $354.00 | |||
ephrin-B3 Antibody (A-7): m-IgG1 BP-HRP Bundle | sc-545260 | 200 µg Ab; 20 µg BP | $354.00 |