FGF-2 Antibody (A-1): sc-271847
- FGF-2 Antibody (A-1) is a mouse monoclonal IgG2a κ, cited in 7 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 35-67 within an internal region of FGF-2 of human origin
- Anti-FGF-2 Antibody (A-1) is recommended for detection of precursor and mature FGF-2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, bovine and porcine
- Anti-FGF-2 Antibody (A-1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of FGF-2 (A-1): sc-271847.
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for FGF-2 Antibody (A-1) for WB applications. This reagent is now offered in a bundle with FGF-2 Antibody (A-1) (see ordering information below).
FGF-2 Antibody (A-1) is a mouse monoclonal IgG2a kappa light chain antibody that detects fibroblast growth factor 2 (FGF-2) protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-FGF-2 antibody (A-1) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. FGF-2 plays a crucial role in various biological processes, including angiogenesis, wound healing, and tissue repair, by promoting cell proliferation and differentiation. FGF-2 is primarily located in the extracellular space and is secreted by a variety of cell types, which is significant because FGF-2 availability in the extracellular environment allows interaction with specific fibroblast growth factor receptors (FGFRs) on target cells, initiating signaling pathways that lead to cellular responses. FGF-2 interaction with receptors is vital for normal development and tissue homeostasis, and dysregulation of this pathway can contribute to pathological conditions such as cancer and cardiovascular diseases. FGF-2 (A-1) monoclonal antibody is an essential tool for researchers studying the FGF signaling pathway and its implications in health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
FGF-2 Antibody (A-1) References:
- TIMP-2 disrupts FGF-2-induced downstream signaling pathways. | Seo, DW., et al. 2008. Microvasc Res. 76: 145-51. PMID: 18721821
- FGF-2 released from degenerating neurons exerts microglial-induced neuroprotection via FGFR3-ERK signaling pathway. | Noda, M., et al. 2014. J Neuroinflammation. 11: 76. PMID: 24735639
- Controlled release of FGF-2 and BMP-2 in tissue engineered periosteum promotes bone repair in rats. | Yin, J., et al. 2018. Biomed Mater. 13: 025001. PMID: 29313523
- Dual roles of endothelial FGF-2-FGFR1-PDGF-BB and perivascular FGF-2-FGFR2-PDGFRβ signaling pathways in tumor vascular remodeling. | Hosaka, K., et al. 2018. Cell Discov. 4: 3. PMID: 29423271
- FGF-2 suppresses expression of nephronectin via JNK and PI3K pathways. | Kato, T., et al. 2018. FEBS Open Bio. 8: 836-842. PMID: 29744297
- FGF-2 signaling activation in the hippocampus contributes to the behavioral and cellular responses to puerarin. | Cheng, J., et al. 2019. Biochem Pharmacol. 168: 91-99. PMID: 31251937
- Core-shell microspheres delivering FGF-2 and BMP-2 in different release patterns for bone regeneration. | Wang, S., et al. 2015. J Mater Chem B. 3: 1907-1920. PMID: 32262263
- FGF-2 release and bonding/physical properties of 4-META/MMA-based adhesive resins incorporating small FGF-2-loaded polymer particles. | Tsuboi, R., et al. 2020. Dent Mater. 36: 1586-1594. PMID: 33019973
- Development of FGF-2-loaded electrospun waterborne polyurethane fibrous membranes for bone regeneration. | Zhang, C., et al. 2021. Regen Biomater. 8: rbaa046. PMID: 33732492
- VEGF and FGF-2 Released In Palatal Suture after Rapid Maxillary Expansion (RME). | Stuani, AS., et al. 2021. Braz Dent J. 32: 98-103. PMID: 33914010
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FGF-2 Antibody (A-1) | sc-271847 | 200 µg/ml | $316.00 | |||
FGF-2 Antibody (A-1): m-IgG Fc BP-HRP Bundle | sc-525830 | 200 µg Ab; 10 µg BP | $354.00 | |||
FGF-2 Antibody (A-1) AC | sc-271847 AC | 500 µg/ml, 25% agarose | $416.00 | |||
FGF-2 Antibody (A-1) HRP | sc-271847 HRP | 200 µg/ml | $316.00 | |||
FGF-2 Antibody (A-1) FITC | sc-271847 FITC | 200 µg/ml | $330.00 | |||
FGF-2 Antibody (A-1) PE | sc-271847 PE | 200 µg/ml | $343.00 | |||
FGF-2 Antibody (A-1) Alexa Fluor® 488 | sc-271847 AF488 | 200 µg/ml | $357.00 | |||
FGF-2 Antibody (A-1) Alexa Fluor® 546 | sc-271847 AF546 | 200 µg/ml | $357.00 | |||
FGF-2 Antibody (A-1) Alexa Fluor® 594 | sc-271847 AF594 | 200 µg/ml | $357.00 | |||
FGF-2 Antibody (A-1) Alexa Fluor® 647 | sc-271847 AF647 | 200 µg/ml | $357.00 | |||
FGF-2 Antibody (A-1) Alexa Fluor® 680 | sc-271847 AF680 | 200 µg/ml | $357.00 | |||
FGF-2 Antibody (A-1) Alexa Fluor® 790 | sc-271847 AF790 | 200 µg/ml | $357.00 | |||
FGF-2 (A-1) Neutralizing Peptide | sc-271847 P | 100 µg/0.5 ml | $68.00 |