GLP-1 Antibody (11E2) is a mouse monoclonal IgG2a antibody that detects glucagon-like peptide-1 (GLP-1) in mouse, rat, human, and bovine samples through western blotting (WB). GLP-1 plays a crucial role in glucose metabolism and appetite regulation, functioning as an incretin hormone that enhances insulin secretion in response to meals while simultaneously inhibiting glucagon release, thereby lowering blood sugar levels. GLP-1 is primarily produced in intestinal L-cells and secreted into the bloodstream, where GLP-1 acts on various tissues, including the pancreas and brain, to exert physiological effects. The localization of GLP-1 in the gut allows for rapid responses to nutrient intake, making GLP-1 a key player in maintaining glucose homeostasis and influencing satiety. Additionally, GLP-1 has been shown to promote pancreatic beta cell proliferation, which is vital for insulin production and overall metabolic health. Anti-GLP-1 antibody (11E2) serves as an essential tool for researchers studying glucose regulation mechanisms and potential therapeutic applications in conditions such as diabetes and obesity.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GLP-1 Antibody (11E2) | sc-80603 | 100 µg/ml | $316.00 |