IFN-γ/Interferon gamma Antibody (B27): sc-52556
- IFN-γ/Interferon gamma Antibody (B27) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against recombinant human IFN-γ expressed by E.coli
- recommended for detection of IFN-γ of human origin by WB, IP, IF and FCM
- available conjugated to FITC for IF, IHC(P) and FCM
- See IFN-γ/Interferon gamma (E-10): sc-373727 for IFN-γ/Interferon gamma antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for IFN-γ/Interferon gamma Antibody (B27). This work is in progress.
IFN-γ Antibody (B27) is a mouse monoclonal IgG1 antibody that detects Interferon (IFN)-γ in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). IFN-γ plays a crucial role in the immune response, acting as an antiviral and antiparasitic agent produced by activated CD4+/CD8+ lymphocytes and natural killer cells. Anti-IFN-γ antibody (B27) helps study IFN-γ′s ability to modulate T cell growth and differentiation while inhibiting B cell proliferation, thereby shaping the adaptive immune response. IFN-γ′s active form is a homodimer, with each subunit comprising six helices, and this dimeric structure is essential for biological activity, as non-covalent interactions stabilize the interface of the helices. The precursor of IFN-γ consists of 166 amino acids, which includes a 23 amino acid secretory sequence, and functionality is further influenced by various post-translational modifications, including glycosylation, leading to multiple forms under non-denaturing conditions, such as dimers and tetramers. The versatility of IFN-γ in immune regulation underscores its significance in therapeutic applications and research, making IFN-γ monoclonal antibody (B27) an invaluable tool for studying immune responses in human samples.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IFN-γ/Interferon gamma Antibody (B27) | sc-52556 | 100 µg/ml | $316.00 | |||
IFN-γ/Interferon gamma Antibody (B27) FITC | sc-52556 FITC | 100 tests in 2 ml | $330.00 |