IFN-γ/Interferon gamma Antibody (A35): sc-52555
- IFN-γ/Interferon gamma Antibody (A35) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against recombinant IFN-γ of human origin
- recommended for detection of IFN-γ of human origin by ELISA
- See IFN-γ/Interferon gamma (E-10): sc-373727 for IFN-γ/Interferon gamma antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for IFN-γ/Interferon gamma Antibody (A35). This work is in progress.
IFN-γ Antibody (A35) is a mouse monoclonal IgG1 antibody that detects Interferon (IFN)-γ in human samples through enzyme-linked immunosorbent assay (ELISA). IFN-γ plays a crucial role in the immune response, acting as a potent antiviral and antiparasitic agent produced by activated CD4+/CD8+ lymphocytes and natural killer cells. Anti-IFN-γ antibody (A35) helps study IFN-γ′s ability to modulate T cell growth and differentiation while inhibiting B cell proliferation, orchestrating a balanced immune response. IFN-γ′s active form is a homodimer, with each subunit comprising six helices, and this dimeric structure is stabilized by non-covalent interactions at the helices′ interface. The precursor of IFN-γ consists of 166 amino acids, which includes a 23 amino acid secretory sequence, and functionality is further enhanced by various post-translational modifications, including glycosylation, which can lead to the formation of multiple isoforms under non-denaturing conditions. These isoforms, including dimers and tetramers, are essential for IFN-γ′s biological activity and stability, making IFN-γ monoclonal antibody (A35) a valuable tool for studying immune responses and related pathologies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IFN-γ/Interferon gamma Antibody (A35) | sc-52555 | 100 µg/ml | $316.00 |