IFN-γ/Interferon gamma Antibody (F-1): sc-57207
- IFN-γ/Interferon gamma Antibody (F-1) is a rat monoclonal IgG2a, cited in 5 publications, provided at 100 µg/ml
- raised against recombinant full length IFN-γ protein of mouse origin
- recommended for detection of recombinant and native IFN-γ of mouse origin by IP, IF and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for IFN-γ/Interferon gamma Antibody (F-1). This work is in progress.
IFN-γ Antibody (F-1) is a rat monoclonal IgG2a antibody that detects Interferon (IFN)-γ in mouse samples through applications such as immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). IFN-γ plays a crucial role in the immune response, acting as an antiviral and antiparasitic agent produced by activated CD4+/CD8+ lymphocytes and natural killer cells. IFN-γ modulates T cell growth and differentiation while inhibiting B cell proliferation, thereby shaping the adaptive immune response. IFN-γ′s active form is a homodimer, with each subunit comprising six helices, and this dimeric structure is stabilized by non-covalent interactions at the interface of the helices. The translated precursor of IFN-γ consists of 166 amino acids, which includes a 23 amino acid secretory sequence, and IFN-γ′s functionality is further enhanced by the presence of multiple forms resulting from variable glycosylation and the formation of dimers and tetramers under non-denaturing conditions. The versatility of IFN-γ in immune modulation underscores its significance in therapeutic applications and research, making anti-IFN-γ antibody (F-1) an essential tool for studying immune responses in mouse models.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IFN-γ/Interferon gamma Antibody (F-1) | sc-57207 | 100 µg/ml | $316.00 |