1-800-457-3801

SCBT Portrait Logo
Seach Input

IGF-1 Receptor α/IGF1R Antibody (G-5): sc-271606

4.9(8)
Write a reviewAsk a question

Datasheets
  • IGF-1 Receptor α/IGF1R Antibody (G-5) is a mouse monoclonal IgG1 κ IGF-1 Receptor α/IGF1R antibody, cited in 12 publications, provided at 200 µg/ml
  • raised against amino acids 123-200 of IGF-IRα of human origin
  • IGF-1 Receptor α/IGF1R Antibody (G-5) is recommended for detection of IGF-IRα of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
  • Anti-IGF-1 Receptor α/IGF1R Antibody (G-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
  • also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of IGF-1 Receptor α/IGF1R (G-5): sc-271606.
  • m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for IGF-1 Receptor α/IGF1R Antibody (G-5) for WB and IHC(P) applications. These reagents are now offered in bundles with IGF-1 Receptor α/IGF1R Antibody (G-5) (see ordering information below).

QUICK LINKS

SEE ALSO...

IGF-IRα Antibody (G-5) is a mouse monoclonal IgG1 kappa light chain antibody that detects IGF-IR alpha in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). IGF-IRα (G-5) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. The insulin-like growth factor-I receptor (IGF-IR) plays a crucial role as a receptor tyrosine kinase, influencing vital cellular processes such as growth, survival, and differentiation. Located on the cell membrane, IGF-IR is activated by insulin-like growth factor-I (IGF-I), which leads to receptor dimerization and autophosphorylation, triggering downstream signaling pathways that include the Ras/ERK and PI3K/Akt pathways. These pathways regulate gene expression and cellular responses to growth signals, making IGF-IR significant in both normal physiology and cancer pathogenesis. The human IGF-IR gene is located on chromosome 15q26.3 and encodes a precursor protein that is cleaved into α and β subunits, highlighting the complexity of structure and function. IGF-IR′s ability to mediate critical growth signals makes anti-IGF-IRα antibody (G-5) valuable for research and clinical applications, particularly in cancer treatment studies.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

IGF-1 Receptor α/IGF1R Antibody (G-5)

sc-271606
200 µg/ml
$316.00

IGF-1 Receptor α/IGF1R Antibody (G-5): m-IgG Fc BP-HRP Bundle

sc-527264
200 µg Ab; 10 µg BP
$354.00

IGF-1 Receptor α/IGF1R Antibody (G-5): m-IgG1 BP-HRP Bundle

sc-532637
200 µg Ab; 20 µg BP
$354.00

IGF-1 Receptor α/IGF1R Antibody (G-5) AC

sc-271606 AC
500 µg/ml, 25% agarose
$416.00

IGF-1 Receptor α/IGF1R Antibody (G-5) HRP

sc-271606 HRP
200 µg/ml
$316.00

IGF-1 Receptor α/IGF1R Antibody (G-5) FITC

sc-271606 FITC
200 µg/ml
$330.00

IGF-1 Receptor α/IGF1R Antibody (G-5) PE

sc-271606 PE
200 µg/ml
$343.00

IGF-1 Receptor α/IGF1R Antibody (G-5) Alexa Fluor® 488

sc-271606 AF488
200 µg/ml
$357.00

IGF-1 Receptor α/IGF1R Antibody (G-5) Alexa Fluor® 546

sc-271606 AF546
200 µg/ml
$357.00

IGF-1 Receptor α/IGF1R Antibody (G-5) Alexa Fluor® 594

sc-271606 AF594
200 µg/ml
$357.00

IGF-1 Receptor α/IGF1R Antibody (G-5) Alexa Fluor® 647

sc-271606 AF647
200 µg/ml
$357.00

IGF-1 Receptor α/IGF1R Antibody (G-5) Alexa Fluor® 680

sc-271606 AF680
200 µg/ml
$357.00

IGF-1 Receptor α/IGF1R Antibody (G-5) Alexa Fluor® 790

sc-271606 AF790
200 µg/ml
$357.00

Could I get a 10ul sample for the IGF1R alpha antibody sample?  GF-IRα Antibody (G-5) sc-271606 200 µg/ml $279.00 ADD TO CART

Asked by: Myungjun Ko
Thank you you for your request. Please contact Technical Service by phone, (800)-457-3801 option 2, email <scbt@scbt.com>, or by live chat directly on our website, www.scbt.com, we would be happy to send you any samples you would like to try, including sc-271606.
Answered by: Tech Service
Date published: 2017-08-14

Can IGF-IRα (G-5): sc-271606 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: Dr Ninau Qelp
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, IGF-IRα (G-5): sc-271606 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-02-24
  • y_2025, m_5, d_6, h_5CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_2
  • loc_en_US, sid_271606, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 104ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by from 検出できましたヒト横紋筋肉腫細胞株RD細胞抽出タンパク質を用いたWBでpro fromとmature formを検出できました
Date published: 2021-12-15
Rated 5 out of 5 by from Good antibody against IGF-IRαThe antibody IGF-IRα (G-5) sc-271606 was tested in a L-MYC murine B cell lymphoma line at 1:50 dilution. Fc-receptor block was performed before surface staining.
Date published: 2019-04-04
Rated 5 out of 5 by from très bon anticorpdétecte de façon très spécifique la forme pro et la chaine alpha d'IGF1R endogène et surexprimé dans les HEK293
Date published: 2018-04-16
Rated 5 out of 5 by from Works great!Works for Immunofluorescence in hES cells at 1:50 dilution
Date published: 2018-03-01
Rated 4 out of 5 by from GoodThis antibody works well in western blotting experiments ofSW480 cell line
Date published: 2017-07-17
Rated 5 out of 5 by from Produced publishable WB data on humanThis IGF-IR monoclonal was referenced in a publication used in WB on SGC7901 cells
Date published: 2017-02-01
Rated 5 out of 5 by from Produced exceptional immunoperoxidase cytoplasmicProduced exceptional immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human heart muscle tissue. -SCBT QC
Date published: 2015-05-21
Rated 5 out of 5 by from LargeLarge, round band in WB in HeLa whole cell lysate. -SCBT QC
Date published: 2014-05-16
  • y_2025, m_5, d_6, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_8
  • loc_en_US, sid_271606, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 16ms
  • REVIEWS, PRODUCT
IGF-1 Receptor α/IGF1R Antibody (G-5) is rated 4.9 out of 5 by 8.
  • y_2025, m_5, d_6, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_8
  • loc_en_US, sid_271606, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 105ms
  • REVIEWS, PRODUCT