4.1R Antibody (D-11) is a mouse monoclonal IgA antibody that detects 4.1R in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). 4.1R is a crucial multifunctional protein that plays a significant role in maintaining the shape and mechanical properties of erythrocyte membranes, which is vital for proper red blood cell function and overall circulatory health. 4.1R is part of the 4.1 gene family, which encodes various cytoskeletal proteins predominantly expressed in the nervous system, including 4.1G, 4.1N, and 4.1B. The unique distribution of 4.1R and 4.1G in the cerebellum suggests their involvement in modulating the mechanical properties of neuronal cell membranes by facilitating the association of fodrin and actin, thereby influencing cellular stability and signaling. Additionally, 4.1R has been associated with hereditary elliptocytosis, highlighting its importance in maintaining erythrocyte integrity. Anti-4.1R antibody (D-11) is particularly valuable for researchers studying red blood cell morphology and related disorders, as well as for those investigating the broader implications of cytoskeletal dynamics in neuronal function.
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Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4.1R Antibody (D-11) | sc-514096 | 200 µg/ml | $316.00 |