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p-Cbl Antibody (pY700.47): sc-136013

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Datasheets
  • p-Cbl Antibody (pY700.47) is a mouse monoclonal IgG1 provided at 50 µg/0.5 ml
  • raised against a short amino acid sequence containing phosphorylated Tyr 700 of Cbl of human origin
  • recommended for detection of Tyr 700 phosphorylated Cbl of mouse, rat and human origin by WB, IP and IF
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for p-Cbl Antibody (pY700.47). This work is in progress.

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    p-Cbl Antibody (pY700.47) is a mouse monoclonal IgG1 antibody that detects p-Cbl in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). p-Cbl monoclonal antibody (pY700.47) recognizes a critical regulator in cellular signaling pathways, particularly in growth factor receptor signaling and immune responses. p-Cbl (pY700.47) antibody targets a protein essential for ubiquitination processes, which regulate protein degradation and modulate various cellular functions, including cell proliferation and differentiation. Phosphorylation of p-Cbl at tyrosine 700 enhances interactions with other signaling proteins, influencing downstream signaling cascades. This post-translational modification proves crucial for proper p-Cbl function by altering protein stability and signal transduction capabilities. p-Cbl (pY700.47) monoclonal antibody serves as an invaluable research tool for studying cellular signaling dynamics and p-Cbl′s role in both normal function and disease states, including cancers where aberrant signaling pathways commonly occur.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    p-Cbl Antibody (pY700.47)

    sc-136013
    50 µg/0.5 ml
    $316.00

    I am using p-Cbl (pY700.47): sc-136013 for immunofluorescence, what dilution of this antibody should I use?

    Asked by: Germaine
    Thank you for your question. We recommend a starting dilution of 1:50. However, optimal antibody concentration should be determined by titration. Please find our full immunofluorescence protocol here: https://www.scbt.com/scbt/resources/protocols/immunofluorescence-cell-staining
    Answered by: Technical Support
    Date published: 2017-03-24
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    Rated 4 out of 5 by from Very robust band in WB in pervanadateVery robust band in WB in pervanadate-treated Jurkat whole cell lysate. -SCBT QC
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    p-Cbl Antibody (pY700.47) is rated 4.0 out of 5 by 1.
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