CYP2S1 Antibody (E-2): sc-398701
- CYP2S1 Antibody (E-2) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 142-300 mapping within an internal region of CYP2S1 of human origin
- recommended for detection of CYP2S1 of human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CYP2S1 Antibody (E-2) for WB applications. These reagents are now offered in bundles with CYP2S1 Antibody (E-2) (see ordering information below).
CYP2S1 Antibody (E-2) is a mouse monoclonal IgG1 antibody that detects CYP2S1 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CYP2S1 is a crucial member of the cytochrome P450 family, specifically classified within the CYP2 subfamily, and plays a significant role in the metabolism of various endogenous and exogenous compounds, including retinoic acid and aromatic hydrocarbons. CYP2S1 is predominantly localized in the endoplasmic reticulum of epithelial cells found in extrahepatic tissues, such as the respiratory and gastrointestinal tracts, as well as the skin, which are often exposed to xenobiotics. CYP2S1 localization allows for efficient metabolism of drugs and other substances, thereby influencing pharmacokinetics and therapeutic responses. CYP2S1 is also implicated in the metabolism of topical medications and has a role in mediating responses to photochemotherapy in conditions like psoriasis. CYP2S1 expression can be induced by dioxin, with regulation occurring through the aryl hydrocarbon receptor and aryl hydrocarbon nuclear translocator pathways, highlighting its importance in environmental and therapeutic contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CYP2S1 Antibody (E-2) | sc-398701 | 200 µg/ml | $316.00 | |||
CYP2S1 Antibody (E-2): m-IgG Fc BP-HRP Bundle | sc-538506 | 200 µg Ab; 10 µg BP | $354.00 | |||
CYP2S1 Antibody (E-2): m-IgGκ BP-HRP Bundle | sc-536132 | 200 µg Ab; 40 µg BP | $354.00 | |||
CYP2S1 Antibody (E-2): m-IgG1 BP-HRP Bundle | sc-545736 | 200 µg Ab; 20 µg BP | $354.00 |