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GGT1 Antibody (3E6) is a mouse monoclonal IgG2a antibody that detects GGT1 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). GGT1 plays a crucial role in the metabolism of glutathione, acting as a glutathionase that facilitates the transfer of the glutamyl moiety of glutathione to amino acids and dipeptides, which is essential for cellular detoxification processes and maintaining redox balance. GGT1 is predominantly located on the outer surface of the cell membrane, where GGT1 is involved in the absorption and secretion of various substances, highlighting its importance in liver function and overall metabolic health. Elevated levels of GGT1 in the bloodstream can serve as an early biomarker for liver damage and hepatocellular carcinoma, making GGT1 a significant target for clinical diagnostics. Notably, GGT1 exhibits marked heterogeneity in human serum and tissues, primarily due to variations in glycosylation rather than differences in gene expression, which underscores the complexity of its regulation and function in different physiological contexts. Anti-GGT1 antibody (3E6) is an invaluable tool for researchers investigating liver diseases and the biochemical pathways involving glutathione metabolism.
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Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GGT1 Antibody (3E6) | sc-100746 | 100 µg/ml | $333.00 |