HSC70/HSP70 Antibody (G-1): sc-137210

HSP 70/HSC 70 Antibody (G-1) is a mouse monoclonal IgG2a antibody that detects HSP 70 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). HSP 70 is a crucial member of the heat shock protein family, known for its role as a molecular chaperone that assists in the proper folding of nascent polypeptide chains and the assembly of multi-protein complexes. HSP 70 is strongly induced in response to heat stress, helping to protect cells from damage caused by misfolded proteins. HSP 70 is predominantly located in the cytosol and nucleus of mammalian cells, where HSP 70 plays a vital role in the cytosolic endoplasmic reticulum and mitochondrial import machinery. HSP 70′s ability to facilitate the translocation of polypeptides across cell membranes and to the nucleus underscores HSP 70′s significance in cellular stress responses and protein homeostasis. Additionally, HSP 70 interacts with various co-chaperones and client proteins, further enhancing HSP 70′s function in maintaining cellular integrity under stress conditions. With versatile applications and critical role in cellular processes, anti-HSP 70 antibody (G-1) is an essential tool for researchers studying protein dynamics and stress responses in a variety of biological contexts.

The preferred HSC70/HSP70 antibody is HSC70/HSP70 Antibody (W27): sc-24.