HSC70/HSP70 Antibody (H-2): sc-137211
- HSC70/HSP70 Antibody (H-2) is a mouse monoclonal IgG2a κ, cited in 4 publications, provided at 200 µg/ml
- raised against amino acids 342-641 mapping at the C-terminus of HSP 70 of human origin
- recommended for detection of HSP 70 and HSC 70 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- See HSC70/HSP70 (W27): sc-24 for HSC70/HSP70 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for HSC70/HSP70 Antibody (H-2) for WB and IHC(P) applications. These reagents are now offered in bundles with HSC70/HSP70 Antibody (H-2) (see ordering information below).
HSP 70/HSC 70 Antibody (H-2) is a mouse monoclonal IgG2a antibody that detects HSP 70 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). HSP 70 is a crucial member of the heat shock protein family, known for its role as a molecular chaperone that assists in the proper folding of nascent polypeptide chains and the assembly of multi-protein complexes. HSP 70 is strongly induced in response to heat stress, helping to protect cells from damage caused by misfolded proteins. HSP 70 and HSC 70 are found in both the cytosol and nucleus of mammalian cells, where these proteins play essential roles in the cytosolic endoplasmic reticulum and mitochondrial import machinery. HSP 70′s ability to facilitate the translocation of polypeptides across cell membranes and into the nucleus underscores HSP 70′s significance in cellular stress responses and protein homeostasis. HSP 70 has been implicated in various cellular processes, including apoptosis and cell signaling, making HSP 70 a vital target for research in stress-related diseases and therapeutic interventions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HSC70/HSP70 Antibody (H-2) | sc-137211 | 200 µg/ml | $316.00 | |||
HSC70/HSP70 Antibody (H-2): m-IgG Fc BP-HRP Bundle | sc-537423 | 200 µg Ab; 10 µg BP | $354.00 | |||
HSC70/HSP70 Antibody (H-2): m-IgGκ BP-HRP Bundle | sc-534681 | 200 µg Ab; 40 µg BP | $354.00 | |||
HSC70/HSP70 Antibody (H-2): m-IgG2a BP-HRP Bundle | sc-548010 | 200 µg Ab; 10 µg BP | $354.00 |