HSP 60 Antibody (A57-E4): sc-57841
- HSP 60 Antibody (A57-E4) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against recombinant serovar A HSP 60 of Chlamydia trachomatis origin
- recommended for detection of an internal region corresponding to amino acids 101-200 of HSP 60 of C. trachomatis origin by WB; also recommended for detection of HSP 60 of C. psittaci, E. coli, S. typhimurium, N. gonorrhoeae, C. burnetii
- See HSP 60 (LK1): sc-59567 for HSP 60 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for HSP 60 Antibody (A57-E4) for WB applications. This reagent is now offered in a bundle with HSP 60 Antibody (A57-E4) (see ordering information below).
HSP 60 Antibody (A57-E4) is a mouse monoclonal IgG1 antibody that detects HSP 60 in C. trachomatis through western blotting (WB). HSP 60, a member of the heat shock protein family, plays a crucial role in the proper folding and assembly of proteins within the mitochondria, which is vital for maintaining cellular function and energy production. HSP 60 acts as a molecular chaperone, ensuring that newly synthesized polypeptides are correctly folded before they enter the mitochondrial matrix, thereby preventing misfolding and aggregation that could lead to cellular stress or apoptosis. HSP 60 is localized in both the mitochondria and the cytosol, highlighting its importance in cellular homeostasis and signaling. The ability of HSP 60 to function as a cell surface marker for γ/δ T cell recognition further underscores its significance in immune responses, making HSP 60 a valuable target for research in both cellular biology and immunology. Anti-HSP 60 antibody (A57-E4) is an essential tool for researchers investigating the roles of molecular chaperones in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HSP 60 Antibody (A57-E4) | sc-57841 | 200 µg/ml | $316.00 | |||
HSP 60 Antibody (A57-E4): m-IgG Fc BP-HRP Bundle | sc-539070 | 200 µg Ab; 10 µg BP | $354.00 |