SP-D Antibody (IIE11): sc-59698
- SP-D Antibody (IIE11) is a mouse monoclonal IgG2b provided at 50 µg/500 µl
- raised against full length native SP-D of rat origin
- recommended for detection of SP-D of mouse, rat and human origin by WB, IF, IHC(P) and ELISA; non cross-reactive with SP-A
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for SP-D Antibody (IIE11). This work is in progress.
SP-D Antibody (IIE11) is a mouse monoclonal IgG2b light chain antibody that detects surfactant protein D (SP-D) in mouse, rat, and human samples through western blotting (WB), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). SP-D is a crucial component of the pulmonary surfactant system, playing a significant role in maintaining surface tension at the air-liquid interface in alveoli, which is vital for effective gas exchange during respiration. SP-D is primarily located in lungs, where SP-D not only aids in reducing surface tension but also functions as an important part of innate immune response. SP-D is a multimeric protein belonging to the collectin family, which means SP-D can bind to carbohydrates on pathogen surfaces, facilitating pathogen clearance and enhancing host defense mechanisms. By recognizing and binding to microbial components, SP-D helps prevent infections in respiratory tract, underscoring SP-D′s importance in both respiratory function and immune protection. SP-D (IIE11) antibody is an essential tool for researchers studying pulmonary surfactant dynamics and immune responses in various species, providing insights into respiratory health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SP-D Antibody (IIE11) | sc-59698 | 50 µg/500 µl | $316.00 |