Dynamin II Antibody (B-4): sc-166525
- Dynamin II Antibody (B-4) is a mouse monoclonal IgG3 κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 853-870 at the C-terminus of Dynamin II of human origin
- recommended for detection of Dynamin II of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, bovine, porcine and canine; may cross-react with Dynamin III
- See Dynamin II (G-4): sc-166669 for Dynamin II antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG3 BP-HRP is the preferred secondary detection reagent for Dynamin II Antibody (B-4) for WB applications. This reagent is now offered in a bundle with Dynamin II Antibody (B-4) (see ordering information below).
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Dynamin II Antibody (B-4) is a mouse monoclonal IgG3 antibody that detects Dynamin II in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Dynamin II plays a crucial role in cellular processes, particularly in endocytosis, where Dynamin II facilitates the scission of newly formed vesicles from the plasma membrane, thereby regulating the internalization of various receptors and signaling molecules. This function is vital for maintaining cellular homeostasis and communication, as Dynamin II allows cells to respond to external signals and modulate their internal environments effectively. Dynamin II is ubiquitously distributed, with the highest expression found in the testis, highlighting Dynamin II′s importance in reproductive biology. Dynamin II contains specific structural domains, including SH3 and proline-rich regions, which are essential for Dynamin II′s interaction with various effector proteins that enhance GTPase activity. These interactions are critical for the rapid endocytosis necessary for synaptic transmission and neurogenesis, making Dynamin II a key player in both neuronal function and overall cellular dynamics. Anti-Dynamin II antibody (B-4) is an invaluable tool for researchers studying these processes and the underlying mechanisms of cellular communication.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Dynamin II Antibody (B-4) | sc-166525 | 200 µg/ml | $316.00 | |||
Dynamin II Antibody (B-4): m-IgG3 BP-HRP Bundle | sc-550393 | 200 µg Ab; 40 µg BP | $354.00 | |||
Dynamin II (B-4) Neutralizing Peptide | sc-166525 P | 100 µg/0.5 ml | $68.00 |