ADAM10 Antibody (A-3): sc-48400
- ADAM10 Antibody (A-3) is a mouse monoclonal IgG2a κ, cited in 30 publications, provided at 200 µg/ml
- raised against amino acids 1-300 of ADAM10 of human origin
- Anti-ADAM10 Antibody (A-3) is recommended for detection of ADAM10 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-ADAM10 Antibody (A-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of ADAM10 (A-3): sc-48400.
- m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for ADAM10 Antibody (A-3) for WB and IHC(P) applications. These reagents are now offered in bundles with ADAM10 Antibody (A-3) (see ordering information below).
ADAM10 Antibody (A-3) is a mouse monoclonal IgG2a kappa light chain antibody that detects ADAM10 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Anti-ADAM10 antibody (A-3) is available in both non-conjugated and multiple conjugated forms, such as agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and various Alexa Fluor® conjugates. ADAM10 plays a crucial role in processing tumor necrosis factor alpha (TNFα), a key cytokine involved in inflammation and immune responses. By cleaving membrane-bound precursor pro-TNF at Ala 76-Val 77, ADAM10 facilitates soluble TNF release, which is essential for regulating inflammatory processes and mediating cell signaling pathways. ADAM10 maintains homeostasis in various physiological processes, including immune response and tissue remodeling. ADAM10 expression occurs in a wide range of tissues, including brain, testis, ovary, and heart, highlighting significance in both normal physiology and potential pathophysiological conditions.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ADAM10 Antibody (A-3) | sc-48400 | 200 µg/ml | $316.00 | |||
ADAM10 Antibody (A-3): m-IgG Fc BP-HRP Bundle | sc-525562 | 200 µg Ab; 10 µg BP | $354.00 | |||
ADAM10 Antibody (A-3): m-IgG2a BP-HRP Bundle | sc-546315 | 200 µg Ab; 10 µg BP | $354.00 | |||
ADAM10 Antibody (A-3) AC | sc-48400 AC | 500 µg/ml, 25% agarose | $416.00 | |||
ADAM10 Antibody (A-3) HRP | sc-48400 HRP | 200 µg/ml | $316.00 | |||
ADAM10 Antibody (A-3) FITC | sc-48400 FITC | 200 µg/ml | $330.00 | |||
ADAM10 Antibody (A-3) PE | sc-48400 PE | 200 µg/ml | $343.00 | |||
ADAM10 Antibody (A-3) Alexa Fluor® 488 | sc-48400 AF488 | 200 µg/ml | $357.00 | |||
ADAM10 Antibody (A-3) Alexa Fluor® 546 | sc-48400 AF546 | 200 µg/ml | $357.00 | |||
ADAM10 Antibody (A-3) Alexa Fluor® 594 | sc-48400 AF594 | 200 µg/ml | $357.00 | |||
ADAM10 Antibody (A-3) Alexa Fluor® 647 | sc-48400 AF647 | 200 µg/ml | $357.00 | |||
ADAM10 Antibody (A-3) Alexa Fluor® 680 | sc-48400 AF680 | 200 µg/ml | $357.00 | |||
ADAM10 Antibody (A-3) Alexa Fluor® 790 | sc-48400 AF790 | 200 µg/ml | $357.00 |