ADAMTS-1 Antibody (30D445.1): sc-52911
- ADAMTS-1 Antibody (30D445.1) is a mouse monoclonal IgM, cited in 1 publications, provided at 100 µl ascites
- raised against synthetic ADAMTS-1 of human origin
- recommended for detection of ADAMTS-1 of mouse, rat and human origin by WB and IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for ADAMTS-1 Antibody (30D445.1). This work is in progress.
ADAMTS-1 Antibody (30D445.1) is a mouse monoclonal IgM antibody that detects ADAMTS-1 protein in mouse, rat, and human samples by western blotting (WB) and immunoprecipitation (IP). Anti-ADAMTS-1 antibody (30D445.1) is available in a non-conjugated form, allowing for versatile research applications. ADAMTS-1, also known as METH-1, C3-C5, and KIAA1346, belongs to a novel protein family characterized by metalloprotease, disintegrin, and Thrombospondin domains. ADAMTS-1 regulates extracellular matrix components and participates in angiogenesis and tissue remodeling. ADAMTS-1 undergoes proteolytic processing after secretion, which is essential for function and activity. A spacer region and Thrombospondin type I motifs at ADAMTS-1′s carboxy-terminus anchor ADAMTS-1 to the extracellular matrix, influencing protein interactions and biological activity. Unique expression patterns of ADAMTS-1 and ADAMTS-2 highlight distinct roles in various tissues and cell types, making these proteins important targets for therapeutic strategies aimed at inhibiting angiogenesis in tumor biology.
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ADAMTS-1 Antibody (30D445.1) References:
- Adamts-1 is essential for the development and function of the urogenital system. | Mittaz, L., et al. 2004. Biol Reprod. 70: 1096-105. PMID: 14668204
- ADAMTS-1/METH-1 and TIMP-3 expression in the primate corpus luteum: divergent patterns and stage-dependent regulation during the natural menstrual cycle. | Young, KA., et al. 2004. Mol Hum Reprod. 10: 559-65. PMID: 15208368
- Full-length ADAMTS-1 and the ADAMTS-1 fragments display pro- and antimetastatic activity, respectively. | Liu, YJ., et al. 2006. Oncogene. 25: 2452-67. PMID: 16314835
- Expression of ADAMTS-1, ADAMTS-4, ADAMTS-5 and TIMP3 by hepatocellular carcinoma cell lines. | Turner, SL., et al. 2012. Int J Oncol. 41: 1043-9. PMID: 22735305
- Role of Versican and ADAMTS-1 in Polycystic Ovary Syndrome. | Özler, S., et al. 2017. J Clin Res Pediatr Endocrinol. 9: 24-30. PMID: 27908842
- Follicular ADAMTS-1 and aggrecan levels in polycystic ovary syndrome. | Tola, EN., et al. 2017. J Assist Reprod Genet. 34: 811-816. PMID: 28417352
- ADAMTS 1, 4, 12, and 13 levels in maternal blood, cord blood, and placenta in preeclampsia. | Namlı Kalem, M., et al. 2018. Hypertens Pregnancy. 37: 9-17. PMID: 29135310
- Abnormal expressions of ADAMTS-1, ADAMTS-9 and progesterone receptors are associated with lower oocyte maturation in women with polycystic ovary syndrome. | GohariTaban, S., et al. 2019. Arch Gynecol Obstet. 299: 277-286. PMID: 30446843
- ADAMTS-1: a novel target gene of an estrogen-induced transcription factor, EGR1, critical for embryo implantation in the mouse uterus. | Park, M., et al. 2021. Cell Biosci. 11: 155. PMID: 34348778
- Expression of ADAMTS 1-4-8 and placental growth factor in ovary and oviduct during pregnancy in the first trimester. | Tatar, M., et al. 2023. Anat Histol Embryol. 52: 619-626. PMID: 37014320
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ADAMTS-1 Antibody (30D445.1) | sc-52911 | 100 µl ascites | $316.00 |