COQ9 Antibody (E-3): sc-271892

COQ9 Antibody (E-3) is a mouse monoclonal IgG2b antibody that detects coenzyme Q9 (COQ9) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). COQ9 is a crucial 318 amino acid protein localized in the mitochondrion, playing a vital role in the biosynthesis of coenzyme Q, which is essential for the electron transport chain and ATP production during aerobic respiration. The proper functioning of COQ9 is significant because COQ9 directly influences cellular energy metabolism, and deficiencies in COQ9 can lead to mitochondrial dysfunction, which is implicated in various neurodegenerative diseases and metabolic disorders. Additionally, multiple isoforms of COQ9 arise from alternative splicing, allowing for diverse regulatory mechanisms that can adapt to different cellular environments and energy demands. The gene encoding COQ9 is located on human chromosome 16, a region associated with several genetic disorders, including giant axonal neuropathy and Rubinstein-Taybi syndrome, highlighting the importance of COQ9 in both health and disease. Anti-COQ9 antibody (E-3) is an invaluable tool for researchers investigating mitochondrial function and related pathologies.

The preferred COQ9 antibody is COQ9 Antibody (G-4): sc-365073.