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DD4 Antibody (WW3) is a mouse monoclonal IgG1 kappa light chain antibody that detects DD4 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Anti-DD4 antibody (WW3) is available as a non-conjugated format. DD4 protein, also known as AKR1C4, is a member of the aldo-keto reductase superfamily and plays a crucial role in steroid hormone and xenobiotic metabolism. Specifically, DD4 is involved in 3-keto-5-dihydrosteroid reduction, which is essential for steroid hormone activity regulation and environmental compound detoxification. This enzymatic activity maintains hormonal balance and protects against potentially harmful substances. While DD1 and DD2 are widely expressed in various tissues, DD4 mRNA expression is predominantly found in the liver, highlighting specialized function in hepatic metabolism. DD4′s ability to interact with NADPH as a cofactor further underscores importance in biochemical pathways that influence both drug metabolism and steroid hormone regulation.
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Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DD4 Antibody (WW3) | sc-100526 | 100 µg/ml | $333.00 |