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PNP Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of PNP Antibodies for the study of purine nucleoside phosphorylase (PNP). PNP Antibodies are available for various research applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Purine nucleoside phosphorylase plays a critical role in purine metabolism, facilitating the conversion of purine nucleosides into their corresponding bases and ribose-1-phosphate. The enzyme maintains the balance of purine nucleotides within cells and is particularly important in the immune system, where it helps regulate lymphocyte proliferation. Dysregulation of PNP can lead to severe immunodeficiency and has been implicated in various diseases, making research into PNP essential for understanding these conditions. Researchers worldwide utilize PNP monoclonal antibodies to advance their studies in cellular metabolism and immune system function. Understanding PNP's role in disease progression helps identify potential therapeutic targets and develop new treatment strategies. Santa Cruz Biotechnology monoclonal antibodies for PNP continue to support breakthrough discoveries in immunology and metabolic research.

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PNP Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

PNP Antibody (F-10)

sc-365551mouse IgG3 κ145-167 (m)WB, IP, IF, ELISAm, r, h

new

(3)

PNP Antibody (D-8)

sc-365132mouse IgG2a κ95-150 (h)WB, IP, IF, ELISAm, r, h

new

(1)

PNP Antibody (D-11)

sc-271890mouse IgG195-150 (h)WB, IP, IF, ELISAm, r, h
1
(1)

PNP Antibody (H-7)

sc-365081mouse IgG2b κ95-150 (h)WB, IP, IF, ELISAm, r, h
2
(2)

PNP CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PNP CRISPR/Cas9 KO Plasmid (h)

sc-404914hGene KnockoutGFP0
(0)

PNP Double Nickase Plasmid (h)

sc-404914-NIChGene KnockoutPuromycin0
(0)

PNP Double Nickase Plasmid (h2)

sc-404914-NIC-2hGene KnockoutPuromycin0
(0)

PNP2 CRISPR/Cas9 KO Plasmid (m)

sc-437104mGene KnockoutGFP0
(0)

PNP2 HDR Plasmid (m)

sc-437104-HDRmHomology Directed RepairPuromycin0
(0)

PNP2 Double Nickase Plasmid (m)

sc-437104-NICmGene KnockoutPuromycin0
(0)

PNP2 Double Nickase Plasmid (m2)

sc-437104-NIC-2mGene KnockoutPuromycin0
(0)

PNP CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PNP CRISPR Activation Plasmid (h)

sc-404914-ACThGene ActivationPuro, Blast, Hygro0
(0)

PNP CRISPR Activation Plasmid (h2)

sc-404914-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

PNP Lentiviral Activation Particles (h)

sc-404914-LAChGene ActivationPuro, Blast, Hygro0
(0)

PNP Lentiviral Activation Particles (h2)

sc-404914-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

PNP2 CRISPR Activation Plasmid (m)

sc-437104-ACTmGene ActivationPuro, Blast, Hygro0
(0)

PNP2 CRISPR Activation Plasmid (m2)

sc-437104-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

PNP2 Lentiviral Activation Particles (m)

sc-437104-LACmGene ActivationPuro, Blast, Hygro0
(0)

PNP2 Lentiviral Activation Particles (m2)

sc-437104-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

PNP siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PNP siRNA (h)

sc-45991hGene SilencingN/A0
(0)

PNP shRNA Plasmid (h)

sc-45991-SHhGene SilencingPuromycin0
(0)

PNP shRNA (h) Lentiviral Particles

sc-45991-VhGene SilencingPuromycin0
(0)

PNP siRNA (m)

sc-45992mGene SilencingN/A0
(0)

PNP shRNA Plasmid (m)

sc-45992-SHmGene SilencingPuromycin0
(0)

PNP shRNA (m) Lentiviral Particles

sc-45992-VmGene SilencingPuromycin0
(0)