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Squalene synthetase Antibody (B-8) is a mouse monoclonal IgG1 antibody that detects Squalene synthetase in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Squalene synthetase plays a crucial role in cholesterol biosynthesis by catalyzing the conversion of transfarnesyl-diphosphate to squalene, marking the first specific step in the cholesterol biosynthetic pathway. This enzyme is strategically located at a branch point in the mevalonate pathway, which is essential for the production of isoprenoids, a class of compounds that are vital for various cellular functions, including membrane integrity and signaling. The importance of Squalene synthetase extends beyond enzymatic activity; anti-Squalene synthetase antibody (B-8) has shown interaction with Squalene epoxidase, another key enzyme in sterol biosynthesis, potentially forming a complex that regulates the rate of cholesterol production. Using Squalene synthetase (B-8) monoclonal antibody enables researchers to gain insights into the dynamics of cholesterol metabolism and its implications in health and disease.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Squalene synthetase Antibody (B-8) | sc-365101 | 200 µg/ml | $316.00 | |||
Squalene synthetase Antibody (B-8): m-IgG Fc BP-HRP Bundle | sc-540311 | 200 µg Ab; 10 µg BP | $354.00 | |||
Squalene synthetase Antibody (B-8): m-IgG1 BP-HRP Bundle | sc-542032 | 200 µg Ab; 20 µg BP | $354.00 | |||
Squalene synthetase (B-8) Neutralizing Peptide | sc-365101 P | 100 µg/0.5 ml | $68.00 |