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LRRK2 Antibodies

Santa Cruz Biotechnology features a diverse variety of LRRK2 monoclonal antibodies for research focused on understanding LRRK2's role in various cellular processes. Multiple detection methods are supported, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). LRRK2, or leucine-rich repeat kinase 2, plays a crucial role in neuronal function and has been linked to Parkinson's disease. The kinase activity of LRRK2 is essential for regulating cellular signaling pathways, and mutations in the LRRK2 gene are among the most common genetic causes of familial and sporadic forms of Parkinson's disease. Understanding LRRK2 function is vital for developing targeted therapies and advancing knowledge of neurodegenerative disorders. Researchers can explore LRRK2's involvement in cellular processes through various experimental approaches. LRRK2 monoclonal antibodies enable detailed investigation of protein localization, expression patterns, and interactions with other molecules. Current research utilizing LRRK2 monoclonal antibodies contributes significantly to advancing our understanding of neurodegenerative diseases and potential therapeutic strategies. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in their mission to unlock new insights into neurological disorders and potential treatments.

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LRRK2 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

LRRK2 Antibody (133AT1218)

sc-130159mouse IgG1 κC-Terminal (h)WB, IP, ELISAm, r, h
2
(2)

LRRK2 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

LRRK2 CRISPR/Cas9 KO Plasmid (h)

sc-402602hGene KnockoutGFP0
(0)

LRRK2 HDR Plasmid (h)

sc-402602-HDRhHomology Directed RepairPuromycin0
(0)

LRRK2 Double Nickase Plasmid (h)

sc-402602-NIChGene KnockoutPuromycin0
(0)

LRRK2 Double Nickase Plasmid (h2)

sc-402602-NIC-2hGene KnockoutPuromycin0
(0)

LRRK2 CRISPR/Cas9 KO Plasmid (m)

sc-426167mGene KnockoutGFP0
(0)

LRRK2 HDR Plasmid (m)

sc-426167-HDRmHomology Directed RepairPuromycin0
(0)

LRRK2 Double Nickase Plasmid (m)

sc-426167-NICmGene KnockoutPuromycin0
(0)

LRRK2 Double Nickase Plasmid (m2)

sc-426167-NIC-2mGene KnockoutPuromycin0
(0)

LRRK2 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

LRRK2 CRISPR Activation Plasmid (h)

sc-402602-ACThGene ActivationPuro, Blast, Hygro0
(0)

LRRK2 CRISPR Activation Plasmid (h2)

sc-402602-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

LRRK2 Lentiviral Activation Particles (h)

sc-402602-LAChGene ActivationPuro, Blast, Hygro0
(0)

LRRK2 Lentiviral Activation Particles (h2)

sc-402602-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

LRRK2 CRISPR Activation Plasmid (m)

sc-426167-ACTmGene ActivationPuro, Blast, Hygro0
(0)

LRRK2 CRISPR Activation Plasmid (m2)

sc-426167-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

LRRK2 Lentiviral Activation Particles (m)

sc-426167-LACmGene ActivationPuro, Blast, Hygro0
(0)

LRRK2 Lentiviral Activation Particles (m2)

sc-426167-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

LRRK2 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

LRRK2 siRNA (h)

sc-45380hGene SilencingN/A0
(0)

LRRK2 shRNA Plasmid (h)

sc-45380-SHhGene SilencingPuromycin0
(0)

LRRK2 shRNA (h) Lentiviral Particles

sc-45380-VhGene SilencingPuromycin0
(0)

LRRK2 siRNA (m)

sc-45750mGene SilencingN/A
3
(0)

LRRK2 shRNA Plasmid (m)

sc-45750-SHmGene SilencingPuromycin
3
(0)

LRRK2 shRNA (m) Lentiviral Particles

sc-45750-VmGene SilencingPuromycin
3
(0)