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AIFL Antibody (A-9) is a mouse monoclonal IgG1 kappa light chain antibody that detects AIFL protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). AIFL Antibody (A-9) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. AIFL, or apoptosis-inducing factor-like, also known as AIFM3, is a 605 amino acid protein primarily localized to the mitochondrion, where AIFL plays a crucial role in apoptosis regulation. AIFL′s mitochondrial localization enables direct influence on mitochondrial membrane potential and facilitates pro-apoptotic factor release, initiating a caspase-dependent apoptotic pathway. AIFL′s function is vital for maintaining cellular homeostasis and preventing uncontrolled cell proliferation, which can lead to cancer. AIFL expression occurs in various tissues, including liver, thymus, ovary, bone marrow, and cerebral cortex, highlighting AIFL′s importance in diverse biological processes. AIFL′s encoding gene is located on human chromosome 22, a region associated with several genetic disorders, including Phelan-McDermid syndrome and Neurofibromatosis type 2, underscoring AIFL′s relevance in both health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
AIFL Antibody (A-9) | sc-376570 | 200 µg/ml | $316.00 | |||
AIFL Antibody (A-9): m-IgGκ BP-HRP Bundle | sc-523012 | 200 µg Ab, 40 µg BP | $354.00 | |||
AIFL Antibody (A-9) AC | sc-376570 AC | 500 µg/ml, 25% agarose | $416.00 | |||
AIFL Antibody (A-9) HRP | sc-376570 HRP | 200 µg/ml | $316.00 | |||
AIFL Antibody (A-9) FITC | sc-376570 FITC | 200 µg/ml | $330.00 | |||
AIFL Antibody (A-9) PE | sc-376570 PE | 200 µg/ml | $343.00 | |||
AIFL Antibody (A-9) Alexa Fluor® 488 | sc-376570 AF488 | 200 µg/ml | $357.00 | |||
AIFL Antibody (A-9) Alexa Fluor® 546 | sc-376570 AF546 | 200 µg/ml | $357.00 | |||
AIFL Antibody (A-9) Alexa Fluor® 594 | sc-376570 AF594 | 200 µg/ml | $357.00 | |||
AIFL Antibody (A-9) Alexa Fluor® 647 | sc-376570 AF647 | 200 µg/ml | $357.00 | |||
AIFL Antibody (A-9) Alexa Fluor® 680 | sc-376570 AF680 | 200 µg/ml | $357.00 | |||
AIFL Antibody (A-9) Alexa Fluor® 790 | sc-376570 AF790 | 200 µg/ml | $357.00 |