p-NHE-3 Antibody (10A8): sc-53961
- p-NHE-3 Antibody (10A8) is a mouse monoclonal IgG2b κ, cited in 8 publications, provided at 200 µg/ml
- raised against a serine-phosphorylated synthetic peptide corresponding to amino acids Ser 605 of NHE-3 of rat origin
- recommended for detection of NHE-3 (phosphoserine 605) of mouse, rat and human origin by WB, IP, IF and IHC(P)
- m-IgGκ BP-HRP is the preferred secondary detection reagent for p-NHE-3 Antibody (10A8) for WB and IHC(P) applications. This reagent is now offered in a bundle with p-NHE-3 Antibody (10A8) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
p-NHE-3 Antibody (10A8) is a mouse monoclonal IgG2b antibody that detects p-NHE-3 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. p-NHE-3, also known as solute carrier family 9 isoform-3 or SLC9A3, plays a crucial role in maintaining ion homeostasis, particularly in the kidney and intestine, where p-NHE-3 mediates sodium absorption. This function is vital for regulating fluid balance and blood pressure, as well as for the overall electrolyte balance in the body. p-NHE-3 is primarily located in the brush border membrane of renal proximal tubule cells and intestinal epithelial cells, where p-NHE-3 activity is essential for the reabsorption of sodium ions and the secretion of hydrogen ions. Proper functioning of p-NHE-3 is critical, as dysregulation can lead to various pathophysiological conditions, including hypertension and metabolic disorders. anti-p-NHE-3 antibody (10A8) is an invaluable tool for researchers studying the physiological and pathological roles of this important protein in various biological contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
p-NHE-3 Antibody (10A8) | sc-53961 | 200 µg/ml | $316.00 | |||
p-NHE-3 Antibody (10A8): m-IgGκ BP-HRP Bundle | sc-534202 | 200 µg Ab; 40 µg BP | $354.00 |