HLA-DQB1 Antibody (IIB3): sc-59247
- HLA-DQB1 Antibody (IIB3) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- raised against HLA-DQB1 of human origin
- recommended for detection of HLA-DQB1 allele DQw1 by IF; may cross-react with DR4, DR7, DRw8 and DRw9
- m-IgG2b BP-HRP is the preferred secondary detection reagent for HLA-DQB1 Antibody (IIB3) for WB and IHC(P) applications. This reagent is now offered in a bundle with HLA-DQB1 Antibody (IIB3) (see ordering information below).
HLA-DQB1 Antibody (IIB3) is a mouse monoclonal IgG2b antibody that detects HLA-DQB1 in human samples through immunofluorescence (IF) applications. HLA-DQB1 is a critical component of the major histocompatibility complex (MHC) class II molecules, which play a vital role in the immune system by presenting peptide antigens to CD4+ T lymphocytes. This interaction is essential for the activation of T cells, which are crucial for orchestrating immune responses against pathogens. The structure of HLA-DQB1 allows binding to a diverse array of peptides, enabling the immune system to recognize and respond to a wide variety of antigens. Variations in the HLA-DQB1 gene have been associated with susceptibility to autoimmune diseases, such as multiple sclerosis and rheumatoid arthritis, highlighting HLA-DQB1′s significance in both health and disease. Anti-HLA-DQB1 antibody (IIB3) is particularly valuable for researchers studying the mechanisms of immune response and the genetic factors influencing autoimmune conditions, providing insights that could lead to novel therapeutic strategies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HLA-DQB1 Antibody (IIB3) | sc-59247 | 200 µg/ml | $316.00 | |||
HLA-DQB1 Antibody (IIB3): m-IgG2b BP-HRP Bundle | sc-548443 | 200 µg Ab; 10 µg BP | $354.00 |