Siglec Antibodies

Santa Cruz Biotechnology delivers a wide array of Siglec monoclonal antibodies for studying sialic acid-binding immunoglobulin-type lectins (Siglecs). Siglec Antibodies are effective tools in various research applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Siglecs play a crucial role in the immune system by regulating cell signaling and modulating immune responses, particularly during inflammation. The ability of Siglecs to recognize sialic acid residues on glycoproteins and glycolipids makes them essential for maintaining self-tolerance and preventing excessive immune activation. Understanding Siglec function is vital for developing therapeutic strategies for various diseases, including cancer and autoimmune disorders. Siglec research has revealed significant insights into immune system regulation and cellular communication pathways. Recent studies have highlighted the importance of Siglecs in neurological development and immune surveillance. Ongoing research continues to uncover new functions and potential therapeutic applications for Siglecs in various disease states. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing scientific understanding of Siglec biology and its implications in human health.