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Fibrillin Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of Fibrillin monoclonal antibodies for investigating fibrillin in various biological processes. Fibrillin monoclonal antibodies are validated for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Fibrillin is a key structural component of microfibrils, which are essential for the integrity and elasticity of connective tissues. Fibrillin plays a central role in the formation of elastic fibers and influences the regulation of growth factors, such as transforming growth factor-beta (TGF-β). Mutations in the fibrillin gene can lead to connective tissue disorders, including Marfan syndrome, making it a crucial area of study in both health and disease. Understanding fibrillin's molecular interactions and cellular distribution helps researchers uncover new therapeutic approaches for connective tissue disorders. Research focusing on fibrillin contributes to breakthroughs in tissue engineering and regenerative medicine. Investigating the relationship between fibrillin and TGF-β signaling pathways reveals important insights into developmental processes and disease mechanisms. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing scientific knowledge of connective tissue biology and related pathologies.

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Fibrillin Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

fibrillin-2 Antibody (H-10)

sc-393968mouse IgG1 κ397-436 (h)WB, IP, IF, ELISAm, r, h
5
(2)

Fibrillin CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

fibrillin-1 CRISPR/Cas9 KO Plasmid (h)

sc-401449hGene KnockoutGFP0
(0)

fibrillin-1 HDR Plasmid (h)

sc-401449-HDRhHomology Directed RepairPuromycin0
(0)

fibrillin-1 Double Nickase Plasmid (h)

sc-401449-NIChGene KnockoutPuromycin0
(0)

fibrillin-1 Double Nickase Plasmid (h2)

sc-401449-NIC-2hGene KnockoutPuromycin0
(0)

fibrillin-1 CRISPR/Cas9 KO Plasmid (m)

sc-420296mGene KnockoutGFP0
(0)

fibrillin-1 HDR Plasmid (m)

sc-420296-HDRmHomology Directed RepairPuromycin0
(0)

fibrillin-1 Double Nickase Plasmid (m)

sc-420296-NICmGene KnockoutPuromycin0
(0)

fibrillin-1 Double Nickase Plasmid (m2)

sc-420296-NIC-2mGene KnockoutPuromycin0
(0)

fibrillin-2 CRISPR/Cas9 KO Plasmid (h)

sc-406714hGene KnockoutGFP0
(0)

fibrillin-2 Double Nickase Plasmid (h)

sc-406714-NIChGene KnockoutPuromycin0
(0)

fibrillin-2 Double Nickase Plasmid (h2)

sc-406714-NIC-2hGene KnockoutPuromycin0
(0)

fibrillin-2 CRISPR/Cas9 KO Plasmid (m)

sc-420297mGene KnockoutGFP0
(0)

fibrillin-2 HDR Plasmid (m)

sc-420297-HDRmHomology Directed RepairPuromycin0
(0)

fibrillin-2 Double Nickase Plasmid (m)

sc-420297-NICmGene KnockoutPuromycin0
(0)

fibrillin-2 Double Nickase Plasmid (m2)

sc-420297-NIC-2mGene KnockoutPuromycin0
(0)

fibrillin-3 CRISPR/Cas9 KO Plasmid (h)

sc-408298hGene KnockoutGFP0
(0)

fibrillin-3 HDR Plasmid (h)

sc-408298-HDRhHomology Directed RepairPuromycin0
(0)

fibrillin-3 Double Nickase Plasmid (h)

sc-408298-NIChGene KnockoutPuromycin0
(0)

fibrillin-3 Double Nickase Plasmid (h2)

sc-408298-NIC-2hGene KnockoutPuromycin0
(0)

Fibrillin CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

fibrillin-1 CRISPR Activation Plasmid (h)

sc-401449-ACThGene ActivationPuro, Blast, Hygro0
(0)

fibrillin-1 CRISPR Activation Plasmid (h2)

sc-401449-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

fibrillin-1 Lentiviral Activation Particles (h)

sc-401449-LAChGene ActivationPuro, Blast, Hygro0
(0)

fibrillin-1 Lentiviral Activation Particles (h2)

sc-401449-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

fibrillin-1 CRISPR Activation Plasmid (m)

sc-420296-ACTmGene ActivationPuro, Blast, Hygro0
(0)

fibrillin-1 CRISPR Activation Plasmid (m2)

sc-420296-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

fibrillin-1 Lentiviral Activation Particles (m)

sc-420296-LACmGene ActivationPuro, Blast, Hygro0
(0)

fibrillin-1 Lentiviral Activation Particles (m2)

sc-420296-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

fibrillin-2 CRISPR Activation Plasmid (h)

sc-406714-ACThGene ActivationPuro, Blast, Hygro0
(0)

fibrillin-2 CRISPR Activation Plasmid (h2)

sc-406714-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

fibrillin-2 Lentiviral Activation Particles (h)

sc-406714-LAChGene ActivationPuro, Blast, Hygro0
(0)

fibrillin-2 Lentiviral Activation Particles (h2)

sc-406714-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

fibrillin-2 CRISPR Activation Plasmid (m)

sc-420297-ACTmGene ActivationPuro, Blast, Hygro0
(0)

fibrillin-2 CRISPR Activation Plasmid (m2)

sc-420297-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

fibrillin-2 Lentiviral Activation Particles (m)

sc-420297-LACmGene ActivationPuro, Blast, Hygro0
(0)

fibrillin-2 Lentiviral Activation Particles (m2)

sc-420297-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

fibrillin-3 CRISPR Activation Plasmid (h)

sc-408298-ACThGene ActivationPuro, Blast, Hygro0
(0)

fibrillin-3 CRISPR Activation Plasmid (h2)

sc-408298-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

fibrillin-3 Lentiviral Activation Particles (h)

sc-408298-LAChGene ActivationPuro, Blast, Hygro0
(0)

fibrillin-3 Lentiviral Activation Particles (h2)

sc-408298-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Fibrillin siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

fibrillin-1 siRNA (h)

sc-43117hGene SilencingN/A0
(0)

fibrillin-1 shRNA Plasmid (h)

sc-43117-SHhGene SilencingPuromycin0
(0)

fibrillin-1 shRNA (h) Lentiviral Particles

sc-43117-VhGene SilencingPuromycin0
(0)

fibrillin-1 siRNA (m)

sc-43118mGene SilencingN/A
2
(0)

fibrillin-1 shRNA Plasmid (m)

sc-43118-SHmGene SilencingPuromycin
2
(0)

fibrillin-1 shRNA (m) Lentiviral Particles

sc-43118-VmGene SilencingPuromycin
2
(0)

fibrillin-2 siRNA (h)

sc-45971hGene SilencingN/A
1
(0)

fibrillin-2 shRNA Plasmid (h)

sc-45971-SHhGene SilencingPuromycin
1
(0)

fibrillin-2 shRNA (h) Lentiviral Particles

sc-45971-VhGene SilencingPuromycin
1
(0)

fibrillin-2 siRNA (m)

sc-45972mGene SilencingN/A0
(0)

fibrillin-2 shRNA Plasmid (m)

sc-45972-SHmGene SilencingPuromycin0
(0)

fibrillin-2 shRNA (m) Lentiviral Particles

sc-45972-VmGene SilencingPuromycin0
(0)

fibrillin-3 siRNA (h)

sc-97083hGene SilencingN/A0
(0)

fibrillin-3 shRNA Plasmid (h)

sc-97083-SHhGene SilencingPuromycin0
(0)

fibrillin-3 shRNA (h) Lentiviral Particles

sc-97083-VhGene SilencingPuromycin0
(0)