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Fibronectin Antibody (A-11) is a mouse monoclonal IgG2b kappa light chain antibody that detects Fibronectin in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Anti-Fibronectin antibody (A-11) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Fibronectin is a crucial extracellular matrix glycoprotein that plays a significant role in cell adhesion, motility, and wound healing, making Fibronectin essential for tissue repair and regeneration. This high molecular weight heterodimeric protein is predominantly located in the extracellular matrix and supports cell attachment and migration. Fibronectin on cell surfaces and in extracellular fluids maintains tissue integrity and facilitates cellular communication. Alternative splicing and post-translational modifications, such as glycosylation, generate various Fibronectin isoforms, some associated with specific tissues or pathological conditions, including malignancies. For example, glycosylated Fibronectin and splice variants have been linked to the myofibroblast phenotype in Dupuytren′s disease, highlighting Fibronectin′s importance in both normal physiology and disease states.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Fibronectin Antibody (A-11) | sc-271098 | 200 µg/ml | $316.00 | |||
Fibronectin Antibody (A-11): m-IgG2b BP-HRP Bundle | sc-548693 | 200 µg Ab; 10 µg BP | $354.00 | |||
Fibronectin Antibody (A-11) AC | sc-271098 AC | 500 µg/ml, 25% agarose | $416.00 | |||
Fibronectin Antibody (A-11) HRP | sc-271098 HRP | 200 µg/ml | $316.00 | |||
Fibronectin Antibody (A-11) FITC | sc-271098 FITC | 200 µg/ml | $330.00 | |||
Fibronectin Antibody (A-11) PE | sc-271098 PE | 200 µg/ml | $343.00 | |||
Fibronectin Antibody (A-11) Alexa Fluor® 488 | sc-271098 AF488 | 200 µg/ml | $357.00 | |||
Fibronectin Antibody (A-11) Alexa Fluor® 546 | sc-271098 AF546 | 200 µg/ml | $357.00 | |||
Fibronectin Antibody (A-11) Alexa Fluor® 594 | sc-271098 AF594 | 200 µg/ml | $357.00 | |||
Fibronectin Antibody (A-11) Alexa Fluor® 647 | sc-271098 AF647 | 200 µg/ml | $357.00 | |||
Fibronectin Antibody (A-11) Alexa Fluor® 680 | sc-271098 AF680 | 200 µg/ml | $357.00 | |||
Fibronectin Antibody (A-11) Alexa Fluor® 790 | sc-271098 AF790 | 200 µg/ml | $357.00 |