Integrin β1/ITGB1 Antibody (JB1B): sc-59829

Integrin β1 Antibody (JB1B) is a mouse monoclonal IgG2a kappa light chain antibody that detects human Integrin β1 by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). Integrin β1 (JB1B) antibody is available in non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Integrin β1 plays a crucial role in cell adhesion and signaling, functioning as a key component of the extracellular matrix interaction. Integrin β1 is primarily located on the cell surface, where Integrin β1 forms heterodimers with various alpha subunits, allowing binding to ligands such as fibronectin, collagen, and vitronectin. This binding is essential for cellular processes such as migration, proliferation, and survival, as binding facilitates communication between the extracellular environment and cell′s internal signaling pathways. Integrin β1′s ability to cluster and activate signaling cascades is vital for maintaining tissue integrity and responding to mechanical stress, making Integrin β1 a significant player in wound healing and immune responses. Anti-Integrin β1 antibody (JB1B) enables researchers to gain insights into the dynamic roles of integrins in cellular behavior and their implications in various diseases, including cancer and fibrosis.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Integrin β1/ITGB1 Antibody (JB1B) has 20 citations in a variety of scientific publications.

Primary antibodies like Anti-Integrin β1/ITGB1 Antibody (JB1B) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Integrin β1/ITGB1 Antibody (JB1B) Specifications

Alternate Product Name: CD29

Product Clone Name: JB1B

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids:

Epitope Target: Integrin β1

Epitope Species: human

Product Reactivity/Detection: Integrin β1

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, FCM

Vialing Information: Each vial contains 200 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 20 citations in various scientific publications

Available Conjugates/Forms for Integrin β1/ITGB1 Antibody (JB1B): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin

The preferred Integrin β1/ITGB1 antibody is Integrin β1/ITGB1 Antibody (K-20): sc-18887.