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β-dystroglycan Antibody (A-9) is a mouse monoclonal IgG1 antibody that detects β-dystroglycan in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). β-dystroglycan plays a crucial role in the structural integrity of muscle cells by forming a vital link between the extracellular matrix and the cytoskeleton, which is essential for maintaining cell shape and stability. β-dystroglycan is primarily located at the sarcolemma of muscle cells, where β-dystroglycan interacts with dystrophin to form the dystrophin-associated protein complex, a key component in muscle function and integrity. Proper localization of β-dystroglycan is critical, as disruptions in β-dystroglycan function or expression can lead to muscular dystrophies and other neuromuscular disorders. Anti-β-dystroglycan antibody (A-9) enables researchers to effectively study β-dystroglycan dynamics in various biological contexts, contributing to a deeper understanding of β-dystroglycan role in muscle physiology and pathology.
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Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
β-dystroglycan Antibody (A-9) | sc-165999 | 200 µg/ml | $316.00 | |||
β-dystroglycan Antibody (A-9): m-IgG Fc BP-HRP Bundle | sc-539984 | 200 µg Ab; 10 µg BP | $354.00 | |||
β-dystroglycan Antibody (A-9): m-IgG1 BP-HRP Bundle | sc-541830 | 200 µg Ab; 20 µg BP | $354.00 |