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Desmin Antibody (D33) is a mouse monoclonal IgG1 antibody that detects Desmin from mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Anti-Desmin antibody (D33) is available in a non-conjugated form, providing flexibility for various experimental needs. Desmin, a 469 amino acid protein, plays a crucial role in maintaining the structural integrity of muscle cells by forming a network of intermediate filaments that connect to the Z line in sarcomeres. This structural arrangement is vital for muscle contraction and force transmission, as Desmin helps to stabilize the myofibrils during muscle activity. Proper functioning of Desmin is essential for muscle health, and mutations in the gene encoding Desmin can lead to severe conditions such as adult-onset skeletal myopathy and cardiac issues. Desmin (D33) antibody enables researchers to effectively study Desmin expression and localization in various tissues, contributing to a better understanding of muscle-related diseases and the cellular mechanisms underlying muscle development and maintenance.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Desmin Antibody (D33) | sc-58744 | 500 µl supernatant | $316.00 |