Lamin A/C Antibody (JoL5): sc-56141
- Lamin A/C Antibody (JoL5) is a mouse monoclonal IgG2a, cited in 1 publications, provided at 500 µl supernatant
- raised against full length Lamin A/C of human origin
- recommended for detection of Lamin A and Lamin C on myoblasts of mouse, rat and human origin by WB, IP, IF and ELISA
- See Lamin A/C (E-1): sc-376248 for Lamin A/C antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Lamin A/C Antibody (JoL5). This work is in progress.
Lamin A/C Antibody (JoL5) is a mouse monoclonal IgG2a antibody that detects Lamin A and Lamin C proteins in myoblasts of mouse, rat, and human origin through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-Lamin A/C antibody (JoL5) is available in a non-conjugated form, providing flexibility for various experimental needs. Lamin A and C proteins play crucial roles in maintaining the structural integrity of the nuclear envelope, which is essential for proper cellular function and morphology. Specifically, Lamin A is involved in organizing chromatin and anchoring nuclear proteins, while Lamin C, a splice variant of Lamin A, shares a significant portion of its sequence but differs at the carboxy-terminus, which may influence its functional properties. The importance of these proteins is underscored by their involvement in various cellular processes, including apoptosis, where Lamin A is cleaved by specific cysteine proteases from the CED-3/ICE family, highlighting their role in regulating cell death and survival. Understanding the dynamics of Lamin A and C is vital for elucidating mechanisms of diseases associated with nuclear envelope dysfunction, making anti-Lamin A/C antibody (JoL5) an invaluable tool for researchers studying these critical cellular components.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Lamin A/C Antibody (JoL5) | sc-56141 | 500 µl supernatant | $316.00 |