Pdcd-2 Antibody (B-4): sc-377250
- Pdcd-2 Antibody (B-4) is a mouse monoclonal IgG1 κ Pdcd-2 antibody, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 315-343 at the C-terminus of Pdcd-2 of human origin
- Pdcd-2 Antibody (B-4) is recommended for detection of Pdcd-2 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-Pdcd-2 Antibody (B-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of Pdcd-2 (B-4): sc-377250.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Pdcd-2 Antibody (B-4). This work is in progress.
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Pdcd-2 Antibody (B-4) is a mouse monoclonal IgG1 kappa light chain antibody that detects Pdcd-2 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-Pdcd-2 antibody (B-4) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Pdcd-2, also known as programmed cell death-2, plays a crucial role in regulating immune responses and is involved in the modulation of programmed cell death pathways. Pdcd-2 is primarily located in the cytoplasm and interacts with various signaling molecules that influence cell survival and apoptosis. Pdcd-2 expression is notably high in tissues such as the placenta, heart, pancreas, lung, and liver, while showing lower levels in the spleen, lymph nodes, and thymus. Understanding Pdcd-2 localization and function is essential, as research may provide insights into immune regulation and potential implications in autoimmune diseases and cancer therapies. Pdcd-2 (B-4) antibody′s ability to detect Pdcd-2 across multiple species makes this reagent valuable for studying function and interactions in various biological contexts.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Pdcd-2 Antibody (B-4) References:
- Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor. | Nishimura, H., et al. 1999. Immunity. 11: 141-51. PMID: 10485649
- PD-L2 is a second ligand for PD-1 and inhibits T cell activation. | Latchman, Y., et al. 2001. Nat Immunol. 2: 261-8. PMID: 11224527
- Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. | Ishida, Y., et al. 1992. EMBO J. 11: 3887-95. PMID: 1396582
- Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes. | Agata, Y., et al. 1996. Int Immunol. 8: 765-72. PMID: 8671665
- Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor Fc(gamma)RIIB. | Ono, M., et al. 1996. Nature. 383: 263-6. PMID: 8805703
- Immunoreceptor tyrosine-based inhibition motifs. | Vivier, E. and Daëron, M. 1997. Immunol Today. 18: 286-91. PMID: 9190115
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Pdcd-2 Antibody (B-4) | sc-377250 | 200 µg/ml | $316.00 | |||
Pdcd-2 Antibody (B-4) AC | sc-377250 AC | 500 µg/ml, 25% agarose | $416.00 | |||
Pdcd-2 Antibody (B-4) HRP | sc-377250 HRP | 200 µg/ml | $316.00 | |||
Pdcd-2 Antibody (B-4) FITC | sc-377250 FITC | 200 µg/ml | $330.00 | |||
Pdcd-2 Antibody (B-4) PE | sc-377250 PE | 200 µg/ml | $343.00 | |||
Pdcd-2 Antibody (B-4) Alexa Fluor® 488 | sc-377250 AF488 | 200 µg/ml | $357.00 | |||
Pdcd-2 Antibody (B-4) Alexa Fluor® 546 | sc-377250 AF546 | 200 µg/ml | $357.00 | |||
Pdcd-2 Antibody (B-4) Alexa Fluor® 594 | sc-377250 AF594 | 200 µg/ml | $357.00 | |||
Pdcd-2 Antibody (B-4) Alexa Fluor® 647 | sc-377250 AF647 | 200 µg/ml | $357.00 | |||
Pdcd-2 Antibody (B-4) Alexa Fluor® 680 | sc-377250 AF680 | 200 µg/ml | $357.00 | |||
Pdcd-2 Antibody (B-4) Alexa Fluor® 790 | sc-377250 AF790 | 200 µg/ml | $357.00 | |||
Pdcd-2 (B-4) Neutralizing Peptide | sc-377250 P | 100 µg/0.5 ml | $68.00 |