CXCR5 Overexpression Lysate (Denatured)

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      H00000643-T01
    • Availability
      Product Discontinued

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CXCR5 Overexpression Lysate (Denatured) Summary

Description
Quality control test: Transient overexpression cell lysate was tested with Anti-CXCR5 antibody by Western Blots. Plasmid: pCMV-CXCR5 full-length
Gene
CXCR5

Applications/Dilutions

Dilutions
  • Western Blot

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, and 0.01% Bromophenol blue).

Lysate Details for Array

Type
Overexpression
Protein State
Denatured

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for CXCR5 Overexpression Lysate (Denatured)

  • BLR1
  • BLR1MDR-15
  • Burkitt lymphoma receptor 1
  • Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif)receptor 5)
  • Burkitt lymphoma receptor 1, GTP-binding protein
  • CD185 antigen
  • CD185
  • chemokine (C-X-C motif) receptor 5
  • C-X-C chemokine receptor type 5
  • CXCR5
  • CXC-R5
  • MDR15CXCR-5
  • MGC117347
  • Monocyte-derived receptor 15

Background

Chemokines play important roles in inflammation and critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors (1). The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. One of the CCR receptors, CCR1, is expressed on neutrophils, monocytes, lymphocytes, and eosinophils and binds the leukocyte chemoattractant and hemopoiesis regulator macrophage-inflammatory protein (MIP-1 ), eotaxin, as well as several other related chemokines (2-4). Mice lacking the chemokine receptor CCR1 have defects in neutrophil trafficking and proliferation (5,6).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.

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Bioinformatics

Gene Symbol CXCR5