Casein Kinase 2 alpha Overexpression Lysate (Denatured) Summary
Description |
Quality control test: Transient overexpression cell lysate was tested with Anti-CSNK2A1 antibody by Western Blots. Plasmid: pCMV-CSNK2A1 full-length |
Gene |
CSNK2A1 |
Applications/Dilutions
Packaging, Storage & Formulations
Storage |
Store at -80C. Avoid freeze-thaw cycles. |
Buffer |
Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, and 0.01% Bromophenol blue). |
Lysate Details for Array
Type |
Overexpression |
Protein State |
Denatured |
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Casein Kinase 2 alpha Overexpression Lysate (Denatured)
Background
Casein kinase I (also designated CKI) and casein kinase II (also designated CKII) compose a family of serine/ threonine protein kinases which are present in all eukaryotes examined to date. CKI family members, which include CKIalpha, gamma, e and delta, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an alpha2beta2 or an alphaalpha'beta2 structure. The a catalytic subunit is stimulated by the beta regulatory subunit, which undergoes autophosphorylation. CKII activity is high in the cytosol and nucleus of proliferating and differentiating cells. CKII is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are
guaranteed for 6 months from date of receipt.
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