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Aldo-keto Reductase 1C1/AKR1C1 293T Cell Transient Overexpression Lysate

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Summary
Reactivity HuSpecies Glossary
Applications WB

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Aldo-keto Reductase 1C1/AKR1C1 293T Cell Transient Overexpression Lysate Summary

Description
Quality control test: Transient overexpression cell lysate was tested with Anti-AKR1C1 antibody by Western Blots. Plasmid: pCMV-AKR1C1 full-length
Specificity
Aldo-keto Reductase 1C1/AKR1C1 293T Cell Transient Overexpression Lysate(Denatured)
Gene
AKR1C1

Applications/Dilutions

Dilutions
  • Western Blot

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)

Lysate Details for Array

Type
293T Cell Transient Overexpression
Protein State
Denatured

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Aldo-keto Reductase 1C1/AKR1C1 293T Cell Transient Overexpression Lysate

  • 20 alpha-hydroxysteroid dehydrogenase
  • 20-ALPHA-HSD
  • 20-alpha-hydroxysteroid dehydrogenase
  • 2-ALPHA-HSD
  • AKR1C1
  • Aldo-keto Reductase 1C1
  • aldo-keto reductase family 1 member C1
  • aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha(3-alpha)-hydroxysteroid dehydrogenase)
  • AldoketoReductase 1C1
  • C9
  • Chlordecone reductase homolog HAKRC
  • DD1/DD2
  • DD1MGC8954
  • DDH1
  • DDHH-37
  • dihydrodiol dehydrogenase 1
  • Dihydrodiol dehydrogenase 1/2
  • dihydrodiol dehydrogenase isoform DD1
  • EC 1.1.1
  • EC 1.1.1.-
  • EC 1.1.1.112
  • EC 1.1.1.149,2-ALPHA-HSD
  • EC 1.3.1.20
  • HAKRC
  • HAKRCDDH1aldo-keto reductase C
  • HBAB
  • hepatic dihydrodiol dehydrogenase
  • High-affinity hepatic bile acid-binding protein
  • Indanol dehydrogenase
  • MBAB
  • Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
  • type II 3-alpha-hydroxysteroid dehydrogenase

Background

AKR1C1 encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.

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Bioinformatics

Gene Symbol AKR1C1