Dvl-3/Dishevelled 3/DVL3 (h): 293T Lysate: sc-114825

The Dvl-3 (h): 293T Lysate is derived from the HEK293T cell line, a human embryonic kidney cell line renowned for its high transfection efficiency and robustness in research applications. This lysate contains Dishevelled-3 (Dvl-3), a crucial protein in the Wnt signaling pathway, which is essential for regulating cell fate, proliferation, and migration. Dvl-3 acts as a key mediator in both the canonical (β-catenin-dependent) and non-canonical (β-catenin-independent) Wnt signaling pathways. It transduces signals from Wnt receptors at the cell surface to downstream effectors in the cytoplasm and nucleus. In research, the Dvl-3 (h): 293T Lysate is extensively used to study the molecular mechanisms of Wnt signaling. Researchers utilize this lysate to investigate protein-protein interactions involving Dvl-3, analyze post-translational modifications, and examine the regulatory mechanisms controlling Dvl-3 activity. It serves as a valuable tool for in vitro assays to screen for potential modulators of Wnt signaling and to explore the role of Dvl-3 in various cellular processes, such as cytoskeletal organization and cell polarity. By leveraging this lysate, scientists can gain deeper insights into the complexities of Wnt signaling and its impact on cellular functions, contributing to the broader understanding of developmental biology and cell signaling networks.